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等级
certified reference material
质量水平
表单
liquid
特点
SNAP-N-SPIKE®, SNAP-N-SHOOT®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
drug control
Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
浓度
1.0 mg/mL in methanol
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
forensics and toxicology
包装形式
single component solution
储存温度
−20°C
SMILES字符串
O=C(NC(C1(CC)C(C)CC)=O)NC1=O
InChI
1S/C10H16N2O3/c1-4-6(3)10(5-2)7(13)11-9(15)12-8(10)14/h6H,4-5H2,1-3H3,(H2,11,12,13,14,15)
InChI key
ZRIHAIZYIMGOAB-UHFFFAOYSA-N
基因信息
human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)
一般描述
应用
- Propranolol-D7 labeled solution: (±)-Propranolol-D₇ used in the analysis of β-blockers and metabolites in milk powder, employing high-performance liquid chromatography coupled to quadrupole Orbitrap high-resolution mass spectrometry. This application underscores the compound′s utility in sophisticated bioanalytical assessments, crucial for understanding pharmacokinetic behaviors in diverse matrices (Cheng et al., 2019).
- Stable isotope-labeled propranolol for bioanalysis: Propranolol-D₇ used as an internal standard in a simultaneous determination method for propranolol and its metabolite in human plasma. The method, utilizing solid phase extraction and liquid chromatography/electrospray tandem mass spectrometry, highlights the role of stable isotopes in enhancing the precision and reliability of pharmacokinetic studies (Partani et al., 2009).
- Propranolol-D₇ tracer for pharmacokinetic studies: (±)-Propranolol-D₇ employed in an innovative technique combining laser microdissection and liquid vortex capture-mass spectrometry for absolute quantitation of propranolol in thin tissue sections. This method allows for precise measurement of drug distribution in small, spatially distinct regions, enhancing the understanding of drug dynamics within organs (Cahill et al., 2016).
法律信息
警示用语:
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
49.5 °F - closed cup
闪点(°C)
9.7 °C - closed cup
法规信息
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