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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
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主要文件

805092

Sigma-Aldrich

PLGA纳米颗粒

100 nm average diameter

别名:

Degradex® PLGA

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5 G
¥301.37
25 G
¥478.72
100 G
¥1,937.50

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5 G
¥301.37
25 G
¥478.72
100 G
¥1,937.50

About This Item

线性分子式:
HO(C3H4O2)x(C2H2O2)yH
UNSPSC代码:
12162002
NACRES:
NA.23

¥301.37


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表单

powder

质量水平

平均直径

100 nm

密度

1.3 g/cm3

运输

wet ice

储存温度

−20°C

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此商品
299693638560843951
assay

98%

assay

98%

assay

97%

assay

-

density

1.259 g/mL at 25 °C (lit.)

density

1.143 g/mL at 25 °C (lit.)

density

1.148 g/mL at 25 °C (lit.)

density

1.259 g/cm3 at 25 °C

form

liquid

form

liquid

form

-

form

liquid

refractive index

n20/D 1.471 (lit.)

refractive index

n20/D 1.467 (lit.)

refractive index

n20/D 1.4470 (lit.)

refractive index

-

bp

105-107 °C/2 mmHg (lit.)

bp

166 °C/18 mmHg (lit.)

bp

76 °C/0.8 mmHg (lit.)

bp

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

一般描述

Degradex®采用聚(D,L-丙交酯--乙交酯)制成,L/G比为50/50,分子量为30,000。
复溶:
  • 从冰柜中取出产品。
  • 等待温度升至环境温度。
  • 向容器中加入去离子水或缓冲液。
  • 涡旋并超声处理5分钟,以确保微球充分混悬。
PLGA纳米颗粒的粒径与稳定剂和聚合物的性质和浓度密切相关。[1][2]

应用

PLGA颗粒可用于药物给药研究中系统相容性的测试。颗粒表面附着药物或生物/化学物质可作为载体。PLGA颗粒用于控释、缓释和靶向给药。一项研究报告了使用PLGA纳米颗粒作为雌激素载体。采用乳化-扩散法制备载药体系。[1][2]

法律信息

Degradex is a registered trademark of Phosphorex, Inc.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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    Preparation of PLGA nanoparticles containing estrogen by emulsification-diffusion method
    Kwon HY, et al.
    Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 182(1-3), 123-130 (2001)
    The Characteristics and Mechanisms of Uptake of PLGA Nanoparticles in Rabbit Conjunctival Epithelial Cell Layers
    Qaddoumi MG, et al.
    Pharmaceut. Res., 21(4), 641-648 null

    商品

    Study on how Degradex® PLGA microspheres and nanoparticles can be used for drug delivery research and formulation development.

    Polymeric antioxidants show promise in drug delivery with superior bioavailability and antioxidant potential.

    Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.

    我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

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