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202444

聚（乙二醇）

Name: 聚（乙二醇）
Brand: ALDRICH

average M_N 3,350, hydroxyl, powder

别名:

PEG

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所有图片(3)

About This Item

线性分子式:

H(OCH₂CH₂)_nOH

CAS号:

25322-68-3

MDL编号:

MFCD00081839

UNSPSC代码:

12352104

PubChem化学物质编号:

24852064

NACRES:

NA.23

product name

聚（乙二醇）, average M_n 3,350, powder

形式

powder

质量水平

200

分子量

average M_n 3,350

pH值（酸碱度）

4.5-7.5

粘度

90 cSt(210 °F) (99 °C)(lit.)

mp

54-58 °C (lit.)

密度

1.204 g/mL at 25 °C

Ω端

hydroxyl

α端

hydroxyl

SMILES字符串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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一般描述

聚乙二醇(PEG)是一种人造生物相容性惰性聚合物，由醚氧(-CH₂-CH₂-O-)重复单元构成。可通过氧乙烯的阴离子聚合反应制得。因具有非免疫原性和高水溶性，广泛用于生物和医学领域。

应用

聚乙二醇可用于修饰磁铁矿纳米粒子。在磁核上涂覆PEG外壳可使纳米粒子在保持磁性的前提下具备良好的稳定性。

PEG可用于修饰光催化TiO₂纳米粉末，用于制造自清洁涂料。PEG涂覆的TiO₂纳米粉末可通过温和条件制备，具有优异的胶体稳定性。

可用作交联剂，制备基于聚N-异丙基丙烯酰胺的热敏型可注射水凝胶。引入PEG提高了水凝胶的化学和机械性能，防止水凝胶在溶胀介质中溶解。这种水凝胶由于生物相容性和生物可降解性，广泛用于生物医学领域。

特点和优势

结构柔性高
生物相容性
水化能力高
无任何空间位阻

其他说明

分子量：M_n 3,015-3,685

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Polyethylene glycol fusion repair prevents reinnervation accuracy in rat peripheral nerve.

Grant A Robinson et al.

Journal of neuroscience research, 94(7), 636-644 (2016-03-21)

Functional recovery following a peripheral nerve injury is made easier when regenerating axons correctly reinnervate their original targets. Polyethylene glycol (PEG) has recently been used in attempts to fuse severed peripheral axons during suture-based repair, but an analysis of target

Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.

Erinna F Lee et al.

Autophagy, 15(5), 785-795 (2019-01-11)

BECN1/Beclin 1 is a critical protein in the initiation of autophagosome formation. Recent studies have shown that phosphorylation of BECN1 by STK4/MST1 at threonine 108 (T108) within its BH3 domain blocks macroautophagy/autophagy by increasing BECN1 affinity for its negative regulators

The AGC Kinase SsAgc1 Regulates Sporisorium scitamineum Mating/Filamentation and Pathogenicity.

Yixu Wang et al.

mSphere, 4(3) (2019-05-31)

Sporisorium scitamineum is the fungal pathogen causing severe sugarcane smut disease that leads to massive economic losses globally. S. scitamineum invades host cane by dikaryotic hyphae, formed after sexual mating of two haploid sporidia of opposite mating type. Therefore, mating/filamentation

[The prevention of the development of the collagen-induced microembolic syndrome by decreasing the hydrodynamic resistance of the blood with special polymers under flow].

I L Konorova et al.

Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)

The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced

Cell-matrix interactions and dynamic mechanical loading influence chondrocyte gene expression and bioactivity in PEG-RGD hydrogels.

Idalis Villanueva et al.

Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)

The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene

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Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

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聚（乙二醇）

average MN 3,350, hydroxyl, powder