Skip to Content

Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

For important updates on recent policy changes, please click here for more details.

Merck
CN

HTR3A

5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

Synonyms:
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Species:
Human HTR3A (3359), Mouse Htr3a (15561), Rat Htr3a (79246), Domestic Rabbit HTR3A (100009570), chicken HTR3A (428247), domestic guinea pig Htr3a (100135547), Horse HTR3A (100009690), naked mole-rat Htr3a (101714088), sheep HTR3A (101110536), dog HTR3A (489399) ...More
UniProtKB ID:
P46098, B4DSY6, G5E986, O60854, Q7KZM7, Q99918, Q9BSZ9
Gene ID:
  • Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
  • Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
  • Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
  • domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Product Number
Description
Species
32473
Metoclopramide, VETRANAL®, analytical standard,
Species
human
BP357
Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human
M1824990
Metoclopramide, European Pharmacopoeia (EP) Reference Standard,
Species
human
S1688
SR 57227A, solid,
Species
human
M0763
Metoclopramide hydrochloride, solid,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
D9190
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
SML0346
Alosetron hydrochloride, ≥98% (HPLC),
Species
human
1478582
Ondansetron hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
PHR1141
Ondansetron Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Y0000196
Ondansetron for TLC system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Y0000197
Ondansetron for LC system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
HPA069442
Anti-HTR3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
ABN1475
Anti-Serotonin receptor 3A/HTR3A, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunohistochemistry
western blot

Small Molecule - Blocker

Product Number
Description
Species
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Species
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Species
human
F2802
Fluvoxamine maleate, solid,
Species
human
S6319
Sertraline hydrochloride, ≥98% (HPLC),
Species
human
C7861
Citalopram hydrobromide, ≥98% (HPLC),
Species
human

Small Molecule - Ligand

Product Number
Description
Species
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

Product Number
Description
Species
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Precursor

Product Number
Description
Species
H9772
5-Hydroxy-L-tryptophan, powder,
Species
human

esiRNA

Product Number
Description
Species
EMU053551
MISSION® esiRNA, targeting mouse Htr3a,
Species
mouse
EHU080571
MISSION® esiRNA, targeting human HTR3A,
Species
human