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Merck
CN

1478582

USP

昂丹司琼 盐酸盐 二水合物

United States Pharmacopeia (USP) Reference Standard

别名:

1,2,3,9-四氢-9-甲基-3-[(2-甲基-1H-咪唑-1-基)甲基] -4H-咔唑-4-酮 盐酸盐, GR 38032F

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About This Item

经验公式(希尔记法):
C18H19N3O · HCl · 2H2O
分子量:
365.85
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

ondansetron

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

Cl[H].[H]O[H].[H]O[H].Cc1nccn1CC2CCc3c(C2=O)c4ccccc4n3C

InChI

1S/C18H19N3O.ClH.2H2O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2;;;/h3-6,9-10,13H,7-8,11H2,1-2H3;1H;2*1H2

InChI key

VRSLTNZJOUZKLX-UHFFFAOYSA-N

基因信息

human ... HTR3A(3359)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

5-HT3 血清素受体拮抗剂

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

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警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Die Pharmazie, 70(3), 183-192 (2015-05-20)
DA-9701, a new prokinetic agent for the treatment of functional dyspepsia, is formulated with Pharbitis semen and Corydalis tuber. This study wasconducted to determine the pharmacological action of DA-9701 and to identify the receptors involved in DA-9701 -induced contractile responsesin
Yoko Nagaya et al.
Drug metabolism and pharmacokinetics, 29(5), 419-426 (2014-05-09)
In central nervous system drug discovery, cerebrospinal fluid (CSF) drug concentration (C(CSF)) has been widely used as a surrogate for unbound brain concentrations (C(u,brain)). However, previous rodent studies demonstrated that when drugs undergo active efflux by transporters, such as P-glycoprotein

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