H8876
5-羟基吲哚-3-乙酸
≥98% (HPLC), crystalline
别名:
5-HIAA
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C10H9NO3
化学文摘社编号:
分子量:
191.18
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
200-195-4
MDL number:
Beilstein/REAXYS Number:
168797
产品名称
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline
Quality Level
InChI key
DUUGKQCEGZLZNO-UHFFFAOYSA-N
InChI
1S/C10H9NO3/c12-7-1-2-9-8(4-7)6(5-11-9)3-10(13)14/h1-2,4-5,11-12H,3H2,(H,13,14)
SMILES string
OC(=O)Cc1c[nH]c2ccc(O)cc12
assay
≥98% (HPLC)
form
crystalline
color
white to purple
mp
161-164 °C (dec.) (lit.)
storage temp.
−20°C
Gene Information
正在寻找类似产品? 访问 产品对比指南
相关类别
Application
5-羟基吲哚-3-乙酸已被用作通过高效液相色谱法（HPLC）测量小鼠脑组织中5-HIAA的标准品。
Biochem/physiol Actions
主要的血清素代谢产物。
General description
5-羧基吲哚-3-乙酸(5-HIAA) 是血清素途径的分解代谢终产物。5-HIAA存在于体液中，如脑脊液（CSF）、血液和尿液。正常患者和癌症患者具有不同的5-HIAA表达水平。墨蝶呤还原酶缺乏可导致脑脊液中的5-HIAA水平降低。患有儿童注意力缺陷多动障碍（ADHD）的1型双相障碍患者的脑脊液5-HIAA水平较低。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Lower CSF HVA and 5-HIAA in bipolar disorder type 1 with a history of childhood ADHD
Ryden E, et al.
Journal of neural transmission (Vienna, Austria : 1996), 116(12), 1667-1674 (2009)
Combining tissue transcriptomics and urine metabolomics for breast cancer biomarker identification
Nam H, et al.
Bioinformatics, 25(23), 3151-3157 (2009)
Progression and recovery of Parkinsonism in a chronic progressive MPTP-induction model in the marmoset without persistent molecular and cellular damage
Franke SK, et al.
Neuroscience, 312, 247-259 (2016)
Chronic high dose of captopril induces depressive-like behaviors in mice: possible mechanism of regulatory T cell in depression
Park HS, et al.
Oncotarget, 8(42), 72528-72543 (2017)
Makoto Tsunoda et al.
Biomedical chromatography : BMC, 33(11), e4650-e4650 (2019-07-18)
Solid-phase extraction technologies are widely used for sample pretreatment in bioanalysis. Monolithic silica disk-packed spin columns modified with phenylboronate moieties have been developed for the selective extraction of cis-diol compounds such as catecholamines. However, in our preliminary studies, serotonin was
商品
Serotonin is stored in cells and metabolized by MAO, influencing CNS, GI, and platelet functions.
血清素（5-羟色胺）主要存在于三种主要细胞类型中：i）中杻神经系统（CNS）和肠肌间神经丛中的血清素能神经元，ii）胃肠道粘膜中的肠嗜铬细胞，和iii）血小板。血清素的代谢主要通过外部线粒体膜酶单胺氧化酶（MAO）进行，它以两种分子亚型存在，分别称为MAO-A和MAO-B。
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持