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Merck
CN

M1824990

甲氧氯普胺

European Pharmacopoeia (EP) Reference Standard

别名:

4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide, Methoxychloroprocainamide

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关于此项目

经验公式(希尔记法):
C14H22ClN3O2
化学文摘社编号:
分子量:
299.80
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1884366
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产品名称

甲氧氯普胺, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)

SMILES string

CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC

InChI key

TTWJBBZEZQICBI-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

metoclopramide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Gene Information

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Application

Metoclopramide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 1


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Robert J Surawski et al.
Psychosomatics, 52(5), 403-409 (2011-09-13)
Metoclopramide is an anti-emetic and gastrointestinal pro-motility agent associated with well-known neuropsychiatric adverse effects, such as dyskinesia, akathisia, and depression. It has never been reported to be associated with homicidal ideation. The authors review the literature on metoclopramide-induced adverse neuropsychiatric
B M Mishriky et al.
British journal of anaesthesia, 108(3), 374-383 (2012-02-07)
Nausea and vomiting occur commonly during and after Caesarean delivery (CD) performed under neuraxial anaesthesia. Metoclopramide is a prokinetic agent reported to be safe in parturients. This meta-analysis assesses the efficacy of metoclopramide for prophylaxis against intra- and postoperative nausea
P Jay Pasricha et al.
Nature clinical practice. Gastroenterology & hepatology, 3(3), 138-148 (2006-03-03)
Metoclopramide, the only drug approved by the FDA for treatment of diabetic gastroparesis, but used off-label for a variety of other gastrointestinal indications, has many potentially troublesome adverse neurologic effects, particularly movement disorders. In this article, we comprehensively review the
Acute dystonic reaction caused by metoclopramide, versus tetanus.
Kyra Dingli et al.
BMJ (Clinical research ed.), 334(7599), 899-900 (2007-04-28)
Paul M Simpson et al.
Emergency medicine Australasia : EMA, 23(4), 452-457 (2011-08-10)
The objective of the present study was to conduct a systematic review and meta-analysis of randomized controlled trials, comparing metoclopramide with placebo, for preventing vomiting in patients who have received i.v. morphine for acute pain in the emergency setting, and

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