推荐产品
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
H2O: >5 mg/mL
创始人
Eisai
SMILES字符串
[Na]NS(=O)(=O)Cc1noc2ccccc12
InChI
1S/C8H7N2O3S.Na/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7;/h1-4H,5H2,(H-,9,11,12);/q-1;+1
InChI key
ZVBIRPKGWOVBLG-UHFFFAOYSA-N
基因信息
human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)
生化/生理作用
Zonisamide sodium salt is an anti-epileptic and also scavenges nitric oxide (NO).
Zonisamide sodium salt is an anti-epileptic. It is effective in various animal epilepsy models and humans with both partial and generalized epileptic seizures. Zonisamide sodium salt also scavenges nitric oxide (NO).
特点和优势
This compound was developed by Eisai. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
Another option for first-line treatment of partial epilepsy?
The Lancet. Neurology, 11(7), 568-569 (2012-06-12)
Journal of clinical psychopharmacology, 32(2), 165-172 (2012-03-01)
Weight gain is commonly observed with olanzapine treatment. Zonisamide is an antiepileptic drug associated with weight loss. This study examined the effectiveness of zonisamide in preventing weight gain in 42 patients beginning olanzapine for bipolar disorder or schizophrenia. Each patient
Epilepsy & behavior : E&B, 23(4), 462-465 (2012-03-13)
Opinions regarding the impact of antiepileptic drugs (AEDs) on the genesis of psychotic symptoms are varied. To re-examine this issue, the records of adult patients with partial epilepsy and newly added AEDs were retrospectively surveyed. The types of newly added
Pharmaceuticals (Basel, Switzerland), 13(5) (2020-05-24)
To understand the pathomechanism and pathophysiology of autosomal dominant sleep-related hypermotor epilepsy (ADSHE), we studied functional abnormalities of glutamatergic transmission in thalamocortical pathway from reticular thalamic nucleus (RTN), mediodorsal thalamic nucleus (MDTN) to orbitofrontal cortex (OFC) associated with S286L-mutant α4β2-nicotinic
Epilepsy & behavior : E&B, 23(4), 497-499 (2012-03-24)
Because iatrogenic obesity may hinder medication compliance, it would be a reasonable approach to consider antiepileptic drugs (AEDs) that promote weight loss in overweight patients. We performed an open-label, observational study to assess the effects of zonisamide on weight in
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