推荐产品
![PI3 kinase [p110a(E545K)/p85a] Active human recombinant, expressed in baculovirus infected insect cells, ≥55% (SDS-PAGE)](/deepweb/assets/sigmaaldrich/product/images/163/742/1cb58aa5-f4e9-4d30-8fb0-4b560e470a03/640/1cb58aa5-f4e9-4d30-8fb0-4b560e470a03.jpg)
一般描述
Human BTK (GenBank Accession No. NM_000061), full length with N-terminal GST-tag, MW= 106 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
应用
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
M Liljeroos et al.
Cellular signalling, 19(3), 625-633 (2006-10-06)
Lipoteichoic acid (LTA) of Gram-positive bacteria initiates innate immune responses via Toll-like receptor-2 (TLR2), resulting in the activation of intracellular signaling and production of inflammatory cytokines in macrophages. Although Bruton's tyrosine kinase (Btk) is biologically important molecule implicated in immune
Ximena Zottig et al.
The protein journal, 36(6), 478-488 (2017-10-05)
Recent investigations of Aneurinibacillus thermoaerophilus strains have allowed identification of a unique solvent tolerant lipase, distinct from known lipases. This work reports the expression and purification of this lipase (LipAT) and the first characterization of its structure and temperature and
L L Ong et al.
SLAS discovery : advancing life sciences R & D, 25(2), 176-185 (2019-11-12)
Protein kinases are intensely studied mediators of cellular signaling. While traditional biochemical screens are capable of identifying compounds that modulate kinase activity, these assays are limited in their capability of predicting compound behavior in a cellular environment. Here, we aim
Niklas Feldhahn et al.
The Journal of experimental medicine, 201(11), 1837-1852 (2005-06-09)
Pre-B cells undergo apoptosis unless they are rescued by pre-B cell receptor-dependent survival signals. We previously showed that the BCR-ABL1 kinase that is expressed in pre-B lymphoblastic leukemia bypasses selection for pre-B cell receptor-dependent survival signals. Investigating possible interference of
Miran Rada et al.
Oncotarget, 8(63), 106639-106647 (2018-01-02)
p53 is a tumour suppressor that is activated in response to various types of stress. It is regulated by a complex pattern of over 50 different post-translational modifications, including ubiquitination by the E3 ligase MDM2, which leads to its proteasomal
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门