Alanine Metabolite Library

Alanine metabolism known also as Glucose-Alanine cycle or Cahill cycle is the process in which muscles utilize amino acids for their energetic needs.

• Glutamate and Pyruvate are transformed into Alanine and α-ketoglutarate in the muscle, through the actions of Alanine aminotransferase (AST) and Pyridoxal Phosphate.
• The α-ketoglutarate transforms to Glutamate through the actions of glutamate dehydrogenase with an addition of ammonia. But, in this pathway, the ammonia is excluded from the muscles.
• The Alanine passes through the blood stream and into the liver. In the liver, the Alanine and a-ketoglutarate transform to Pyruvate and Glutamate by the actions of Alanine aminotransferase (AST).
• The Pyruvate transforms to glucose by the Cori cycle (Gluconeogenesis) and returns to the muscle from the blood stream.

Components:

Each vial is packaged individually and contains 10 mg of the Alanine pathway metabolite standards.