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Merck
CN
所有图片(1)

主要文件

G8171

Sigma-Aldrich

藤黄酸

≥95% (HPLC), powder

别名:

β-藤黄酸, 1,5-甲醇-1H,3H,11H-呋喃(3,4-g)吡喃(3,2-b)氧杂蒽-1-巴豆酸, B"-Guttiferrin, 藤黄酸

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选择尺寸

10 μG
¥5,685.79

¥5,685.79


预计发货时间2025年5月06日详情

针对您的靶标提供了无防腐剂重组抗体。欢迎选购 ZRB1119

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选择尺寸

变更视图
10 μG
¥5,685.79

About This Item

经验公式(希尔记法):
C38H44O8
CAS号:
分子量:
628.75
UNSPSC代码:
12352200
PubChem化学物质编号:

¥5,685.79


预计发货时间2025年5月06日详情

针对您的靶标提供了无防腐剂重组抗体。欢迎选购 ZRB1119

获取大包装报价

质量水平

方案

≥95% (HPLC)

表单

powder

颜色

yellow to orange

溶解性

DMSO: ≥10 mg/mL
H2O: insoluble

储存温度

−20°C

SMILES字符串

C\C(C)=C\CC[C@@]1(C)Oc2c(C\C=C(\C)C)c3O[C@@]45[C@@H]6C[C@@H](C=C4C(=O)c3c(O)c2C=C1)C(=O)[C@]5(C\C=C(\C)C(O)=O)OC6(C)C

InChI

1S/C38H44O8/c1-20(2)10-9-15-36(8)16-14-24-29(39)28-30(40)26-18-23-19-27-35(6,7)46-37(33(23)41,17-13-22(5)34(42)43)38(26,27)45-32(28)25(31(24)44-36)12-11-21(3)4/h10-11,13-14,16,18,23,27,39H,9,12,15,17,19H2,1-8H3,(H,42,43)/b22-13-/t23-,27+,36-,37+,38-/m1/s1

InChI key

GEZHEQNLKAOMCA-RRZNCOCZSA-N

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此商品
806811806900806765
二氧化硅 mesoporous, 1 μm particle size, pore size ~4 nm

806889

二氧化硅

二氧化硅 mesoporous, 1 μm particle size, pore size ~2 nm

806811

二氧化硅

二氧化硅 mesoporous, 2 μm particle size, pore size ~4 nm

806900

二氧化硅

二氧化硅 mesoporous, 3 μm particle size, pore size ~2 nm

806765

二氧化硅

form

mesoporous, powder

form

powder

form

mesoporous, powder

form

mesoporous, powder

assay

99.9% trace metals basis

assay

99.9% trace metals basis

assay

99.9% trace metals basis

assay

99.9% trace metals basis

particle size

1 μm

particle size

1 μm

particle size

2 μm

particle size

3 μm

mp

>1600 °C (lit.)

mp

>1600 °C (lit.)

mp

>1600 °C (lit.)

mp

>1600 °C (lit.)

surface area

300-400 m2/g

surface area

1000 ± 100 m2/g

surface area

300-400 m2/g

surface area

-

pore size

0.2-0.4 cm3/g pore volume

pore size

0.1-0.3 cm3/g pore volume, 1.9-2.3 nm pore diameter, ~2 nm pore size

pore size

0.2-0.4 cm3/g pore volume, ~4 nm pore size

pore size

0.1-0.3 cm3/g pore volume, ~2 nm pore size

生化/生理作用

藤黄酸可作为半胱天冬酶活化剂和细胞凋亡诱导剂。
藤黄酸可作为半胱天冬酶活化剂和细胞凋亡诱导剂,在细胞周期的G2/M期引起不可逆的停滞。

特点和优势

该化合物在受体分类和信号转导手册的 半胱天冬酶 页面上有详细描述。如需浏览其他手册页面,请点击此处

象形图

Skull and crossbones

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


  • 历史批次信息供参考:

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    Li-jing Yang et al.
    Acta pharmacologica Sinica, 34(2), 191-198 (2013-01-01)
    Gambogic acid (GA) is the main active ingredient of gamboge, a brownish to orange dry resin secreted from Garcinia hanburyi, a plant that is widely distributed in nature. Recent in vitro and in vivo studies have demonstrated that GA exerts
    Tao Chen et al.
    Molecules (Basel, Switzerland), 17(6), 6249-6268 (2012-05-29)
    Gambogic acid (GA) is in a phase II clinical trial as an antitumor and antiangiogenesis agent. In this study, 36 GA derivatives were synthesized and screened in a zebrafish model to evaluate their antiangiogenic activity and toxicity. Derivatives 4, 32
    Lianghua Fang et al.
    International journal of nanomedicine, 7, 4109-4118 (2012-08-14)
    The present study evaluated whether magnetic nanoparticles containing Fe(3)O(4) could enhance the activity of gambogic acid in human colon cancer cells, and explored the potential mechanisms involved. Cytotoxicity was evaluated by MTT assay. The percentage of cells undergoing apoptosis was
    Xu Wang et al.
    Anti-cancer agents in medicinal chemistry, 12(8), 994-1000 (2012-02-22)
    Gambogic acid (GA) is a caged xanthone that is derived from Garcinia hanburyi and functions as a strong apoptotic inducer in many types of cancer cells. The distinct effectiveness of GA has led to its characterization as a novel anti-cancer
    Gianni Guizzunti et al.
    Chembiochem : a European journal of chemical biology, 13(8), 1191-1198 (2012-04-26)
    The natural product gambogic acid (GA) has shown significant potential as an anticancer agent as it is able to induce apoptosis in multiple tumor cell lines, including multidrug-resistant cell lines, as well as displaying antitumor activity in animal models. Despite

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