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Merck
CN

45125

Sigma-Aldrich

弹性蛋白酶 来源于猪胰腺

lyophilized, powder, white, ~8 U/mg

别名:

弹性蛋白酶 来源于猪胰腺, 胰酞酶 E

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About This Item

CAS号:
EC 号:
MDL编号:
UNSPSC代码:
12352204

生物来源

Porcine pancreas

质量水平

表单

powder

质量

lyophilized

比活

~8 U/mg

分子量

Mr ~25000

杂质

salt, none detected

颜色

white

储存温度

−20°C

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生化/生理作用

弹性蛋白酶水解弹性蛋白(弹性纤维的特定蛋白质)并消化血红蛋白、酪蛋白和纤维蛋白。

单位定义

一个单元将在 25℃ 下,每分钟,pH8.0,水解 1.0 μmole 的 N-琥珀酰-L-Ala-Ala-Ala-对硝基苯胺。
1 U corresponds to the amount of enzyme which liberates 1 μmol 4-nitroaniline per minute at 25°C and pH 7.8 (succinyl-(L-Ala)3-4-nitroanilide as substrate)

其他说明

For protein sequence studies, limited proteolysis; Application in (selective) hydrolysis/condensation of carboxylic ester bonds
Sales restrictions may apply

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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I Grunnet et al.
The Biochemical journal, 209(1), 215-222 (1983-01-01)
Fatty acid synthetase from goat mammary gland was subjected to limited proteolysis by trypsin and elastase. Both proteolytic enzymes selectively cleaved the chain-terminating thioester hydrolase component from the enzyme complex, leaving all other partial activities intact in the core peptides.
T. Sakurai et al.
Journal of the American Chemical Society, 110, 7236-7236 (1988)
Commentary on 'Performance of a modified rabbit model of abdominal aortic aneurysm induced by topical application of porcine elastase: 5-month follow-up study'.
G W Cockerill
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 45(2), 153-153 (2013-01-02)
Gerwin E Engels et al.
Journal of cardiothoracic surgery, 8, 4-4 (2013-01-11)
Despite continuous improvements in materials and perfusion techniques, cardiac surgery still causes lung injury and a delay of pulmonary recovery. Currently, there is no gold standard for quantifying cardiac surgery induced lung injury and dysfunction. Adding objective measures, such as
Etsuko Kurimoto et al.
Respiratory research, 14, 5-5 (2013-01-22)
Pulmonary emphysema is characterized by alveolar destruction and persistent inflammation of the airways. Although IL-17A contributes to many chronic inflammatory diseases, it's role in the inflammatory response of elastase-induced emphysema remains unclear. In a model of elastase-induced pulmonary emphysema we

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