T3937
丁卡因 盐酸盐
meets USP testing specifications
别名:
4-(丁氨基)-苯甲酸-2-(二甲氨基)乙酯, 丁卡因 盐酸盐
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关于此项目
经验公式（希尔记法）:
C15H24N2O2 · HCl
化学文摘社编号:
分子量:
300.82
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H
SMILES string
Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C
InChI key
PPWHTZKZQNXVAE-UHFFFAOYSA-N
agency
meets USP testing specifications
application(s)
pharmaceutical (small molecule)
Quality Level
Gene Information
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Application
眼用局部麻醉药；用于脊髓麻醉
Biochem/physiol Actions
阻断 Ca2+ 从肌浆网的电压敏感性释放。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
target_organs
Central nervous system
Zachery Koneval et al.
Epilepsia, 61(9), 2022-2034 (2020-08-07)
Initial identification of new investigational drugs for the treatment of epilepsy is commonly conducted in well-established mouse acute and chronic seizure models: for example, maximal electroshock (MES), 6 Hz, and corneal kindling. Comparison of the median effective dose (ED50) of approved
Gabriel C Gaviola et al.
The Laryngoscope, 123(4), 852-858 (2013-02-14)
Transnasal endoscopy is commonly performed in an outpatient otolaryngology setting. Patients are typically administered a topical anesthetic and decongestant prior to this procedure to alleviate discomfort and improve visualization. There is no consensus on which topical anesthetic is most effective
Patrick E McCleskey et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 39(1 Pt 1), 82-91 (2013-01-03)
Few published studies have analyzed serum lidocaine levels and individual patient characteristics affecting metabolism after application of compounded topical anesthetics. To measure serum lidocaine levels during and cutaneous side effects after standardized application of 23% lidocaine/7% tetracaine compounded anesthetic to
K Ruetzler et al.
British journal of anaesthesia, 109(5), 790-796 (2012-07-27)
Arterial catheterization is painful and is associated with patient stress and anxiety. Analgesia is usually provided by subcutaneous injection of local anaesthetic. An alternative is topical anaesthesia, such as Rapydan which is a novel topical anaesthetic patch containing 70 mg
Quan Wen et al.
Cornea, 32(2), 179-184 (2012-08-08)
Our recent tissue cross-linking studies have raised the possibility of using aliphatic β-nitroalcohols (BNAs) for pharmacologic, therapeutic corneal cross-linking. The present study was performed to determine the permeability of BNAs and to explore the use of permeability-enhancing agents. Ex vivo
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