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Merck
CN

RDD040

Sigma-Aldrich

十二烷基硫酸钠

BioReagent, suitable for electrophoresis, for molecular biology, ≥98.5% (GC), free-flowing, Redi-Dri

别名:

SDS, 十二烷基硫酸盐 钠盐, 十二烷基硫酸钠, 月桂基硫酸盐 钠盐, 月桂基硫酸钠

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About This Item

线性分子式:
CH3(CH2)11OSO3Na
CAS号:
分子量:
288.38
Beilstein:
3599286
MDL编号:
UNSPSC代码:
12161900
NACRES:
NA.25

等级

for molecular biology

质量水平

描述

anionic

产品线

BioReagent
Redi-Dri

方案

≥98.5% (GC)

质量

free-flowing

分子量

micellar 18,000

聚集数

62

技术

electrophoresis: suitable

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

转变温度

cloud point >100 °C

溶解性

water: soluble

痕量阴离子

chloride (Cl-): ≤500 ppm
phosphate (PO43-): ≤10 ppm

痕量阳离子

heavy metals (as Pb): ≤10 ppm

吸附

≤0.1 at 260 at 3%
≤0.1 at 280 at 3%

HLB

40

适用性

suitable for electrophoresis

异质活性

DNase, RNase, none detected

SMILES字符串

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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一般描述

Sodium dodecyl sulfate (SDS) is an amphipathic detergent commonly used for denaturing proteins. SDS has a long-chain aliphatic group, with negatively charged sulfate groups that coat the surface of proteins, causing them to lose their quaternary structure.

应用

十二烷基硫酸钠已用于:
  • 染色体免疫沉淀
  • SDS-聚丙烯酰胺凝胶电泳(SDS-PAGE)
  • 作为用于免疫印迹的放射免疫沉淀检测缓冲液的一种组分
阴离子洗涤剂

分析说明

针对用于变性聚丙烯酰胺凝胶电泳进行了测试。

其他说明

For additional information on our range of Biochemicals, please complete this form.

法律信息

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

警示用语:

Danger

危险分类

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

4.1B - Flammable solid hazardous materials

WGK

WGK 2

闪点(°F)

338.0 °F

闪点(°C)

170 °C

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Bipolar disorder (BD) is a heritable neuropsychiatric disorder with largely unknown pathogenesis. Given their prominent role in brain function and disease, we hypothesized that microRNAs (miRNAs) might be of importance for BD. Here we show that levels of miR-34a, which
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Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 30(2), 318-329 (2014-08-27)
Transforming growth factor (TGF)-β signaling plays critical roles during skeletal development and its excessive signaling causes genetic diseases of connective tissues including Marfan syndrome and acromelic dysplasia. However, the mechanisms underlying prevention of excessive TGF-β signaling in skeletogenesis remain unclear.

商品

Redi-Dri™ prevents hygroscopic powders, such as inorganic salts, from absorbing moisture and forming clumps, leaving the salts free-flowing every time.

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