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Merck
CN
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文件

安全信息

Q5001

Supelco

喹尼丁 葡糖酸盐

analytical standard

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经验公式（希尔记法）:
C20H24N2O2 · C6H12O7
CAS号:
7054-25-3
分子量:
520.57
EC 号:
230-333-9
MDL编号:
MFCD00067566
UNSPSC代码:
41116107
PubChem化学物质编号:
329823867
NACRES:
NA.24

等级

analytical standard

质量水平

100

技术

HPLC: suitable
gas chromatography (GC): suitable

杂质

≤20% Dihydroquinidine (according to USP specifications., actual content given on label)

应用

food and beverages

格式

neat

SMILES字符串

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.[H][C@@]12CCN(C[C@@H]1C=C)[C@]([H])(C2)[C@@H](O)c3ccnc4ccc(OC)cc34

InChI

1S/C20H24N2O2.C6H12O7/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;7-1-2(8)3(9)4(10)5(11)6(12)13/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;2-5,7-11H,1H2,(H,12,13)/t13-,14-,19+,20-;2-,3-,4+,5-/m01/s1

InChI key

XHKUDCCTVQUHJQ-LCYSNFERSA-N

基因信息

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生化/生理作用

IA 类抗心律失常药；钾通道阻断剂。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302 + H312 + H332

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

监管及禁止进口产品

分析证书(COA)

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K D Miller et al.
The New England journal of medicine, 321(2), 65-70 (1989-07-13)
During the past decade the incidence of Plasmodium falciparum malaria in the United States has increased 10-fold. Treatment may be delayed because the therapy recommended for severe or complicated disease, intravenous quinine dihydrochloride, is available only from the Centers for
Proarrhythmia: disparity of programmed electrical stimulation results and spontaneous occurrence: a case report.
A E Alicea et al.
Maryland medical journal (Baltimore, Md. : 1985), 40(6), 521-523 (1991-06-01)
D J Weiss et al.
Journal of the American Veterinary Medical Association, 196(3), 472-475 (1990-02-01)
Records of 8 dogs with drug-associated aplastic anemia were reviewed. Drugs suspected as being causative included estradiol cyclopentylpropionate (3 dogs), phenylbutazone (2 dogs), meclofenamic acid (1 dog), trimethoprim-sulfadiazine and fenbendazole (1 dog), and quinidine (1 dog). Five of the dogs
A Garg et al.
Journal of cardiovascular electrophysiology, 9(6), 642-647 (1998-07-08)
A case is presented of an 18-year-old male who had been resuscitated following an episode of sudden death due to ventricular fibrillation. The patient was noted to have an abnormal deflection in the terminal QRS on surface ECG and an
D Darbar et al.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 53(6), 655-658 (1996-03-15)
The effect of a polyvinyl chloride (PVC) i.v. administration system on the availability of quinidine gluconate was studied. Quinidine gluconate diluted in 5% dextrose injection was administered intravenously to five healthy volunteers via conventional PVC infusion sets, and the subjects
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