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Merck
CN

Q5001

喹尼丁 葡糖酸盐

analytical standard

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关于此项目

经验公式(希尔记法):
C20H24N2O2 · C6H12O7
化学文摘社编号:
分子量:
520.57
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
230-333-9
MDL number:
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InChI key

XHKUDCCTVQUHJQ-LCYSNFERSA-N

InChI

1S/C20H24N2O2.C6H12O7/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;7-1-2(8)3(9)4(10)5(11)6(12)13/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;2-5,7-11H,1H2,(H,12,13)/t13-,14-,19+,20-;2-,3-,4+,5-/m01/s1

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.[H][C@@]12CCN(C[C@@H]1C=C)[C@]([H])(C2)[C@@H](O)c3ccnc4ccc(OC)cc34

grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤20% Dihydroquinidine (according to USP specifications., actual content given on label)

application(s)

food and beverages

format

neat

Quality Level

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

IA 类抗心律失常药;钾通道阻断剂。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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D J Weiss et al.
Journal of the American Veterinary Medical Association, 196(3), 472-475 (1990-02-01)
Records of 8 dogs with drug-associated aplastic anemia were reviewed. Drugs suspected as being causative included estradiol cyclopentylpropionate (3 dogs), phenylbutazone (2 dogs), meclofenamic acid (1 dog), trimethoprim-sulfadiazine and fenbendazole (1 dog), and quinidine (1 dog). Five of the dogs
D Darbar et al.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 53(6), 655-658 (1996-03-15)
The effect of a polyvinyl chloride (PVC) i.v. administration system on the availability of quinidine gluconate was studied. Quinidine gluconate diluted in 5% dextrose injection was administered intravenously to five healthy volunteers via conventional PVC infusion sets, and the subjects
P T Holzberger et al.
American heart journal, 136(1), 49-56 (1998-07-17)
Intravenous procainamide hydrochloride is frequently used in the acute care setting and during electrophysiologic testing, but intravenous quinidine gluconate is rarely used because of concerns about its safety. This study prospectively compares the hemodynamic and electrophysiologic effects of these agents
A Garg et al.
Journal of cardiovascular electrophysiology, 9(6), 642-647 (1998-07-08)
A case is presented of an 18-year-old male who had been resuscitated following an episode of sudden death due to ventricular fibrillation. The patient was noted to have an abnormal deflection in the terminal QRS on surface ECG and an
K D Miller et al.
The New England journal of medicine, 321(2), 65-70 (1989-07-13)
During the past decade the incidence of Plasmodium falciparum malaria in the United States has increased 10-fold. Treatment may be delayed because the therapy recommended for severe or complicated disease, intravenous quinine dihydrochloride, is available only from the Centers for

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