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PHR1129

Supelco

丁卡因 盐酸盐

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

4-(丁氨基)-苯甲酸-2-(二甲氨基)乙酯, 丁卡因 盐酸盐

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About This Item

经验公式（希尔记法）:
C15H24N2O2 · HCl
CAS号:
136-47-0
分子量:
300.82
MDL编号:
MFCD00038912
UNSPSC代码:
41116107
PubChem化学物质编号:
329823150
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. T0500000
traceable to USP 1650006

API类

tetracaine

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-30°C

SMILES字符串

Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C

InChI

1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H

InChI key

PPWHTZKZQNXVAE-UHFFFAOYSA-N

基因信息

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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相关类别

一般描述

Tetracaine hydrochloride is a local anesthetic drug and an ester derivative of p-amino benzoic acid. It acts by interfering with the entry of sodium ions into nerve cells and is one of the commonly used topical anesthetics.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Tetracaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
眼用局部麻醉药；用于脊髓麻醉

生化/生理作用

阻断 Ca2+ 从肌浆网的电压敏感性释放。

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA7150 in the slot below. This is an example certificate only and may not be the lot that you receive.

相关产品

产品编号
说明
价格

1650006

丁卡因 盐酸盐, United States Pharmacopeia (USP) Reference Standard

T0500000

丁卡因 盐酸盐, European Pharmacopoeia (EP) Reference Standard

Y0001002

丁卡因 盐酸盐, European Pharmacopoeia (EP) Reference Standard

1649991

丁卡因, United States Pharmacopeia (USP) Reference Standard

1650017

4-(丁基氨基)苯甲酸, United States Pharmacopeia (USP) Reference Standard

1650028

Tetracaine Related Compound C, United States Pharmacopeia (USP) Reference Standard

1466572

4-硝基苯甲酸, United States Pharmacopeia (USP) Reference Standard

Y0002117

丁卡因, European Pharmacopoeia (EP) Reference Standard

PHR9019

4-氨基苯甲醇, reference material

PHR9024

3-氨基苯甲醇, reference material

PHR2236

丁卡因相关化合物B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2261

Tetracaine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2339

4-硝基苯甲酸, Pharmaceutical Secondary Standard; Certified Reference Material

PHR3140

丁卡因, pharmaceutical secondary standard, certified reference material

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H301,H319,H336

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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分析证书(COA)

Lot/Batch Number

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访问文档库

Local Anesthetic Pharmacology
Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 206-220 (2017)
Tetracaine hydrochloride
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 4106-4106 (2018)
14 - Local Anesthetics
Pharmacology and Therapeutics for Dentistry, 206-220 (2017)
Determination of Two Components in Tetracaine Hydrochloride Eye Drops by HPLC [J]
Yahong L, et al.
Chinese Pharmaceutical Journal, 14(2), 381-386 (2009)
Tetracaine hydrochloride
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3742-3743 (2017)
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