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P8136

Sigma-Aldrich

聚乙烯醇

87-90% hydrolyzed, average mol wt 30,000-70,000

别名:

PVA, PVAl, PVOH, Poly(Ethenol)

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About This Item

线性分子式:
[-CH2CHOH-]n
CAS号:
9002-89-5
MDL编号:
MFCD00081922
UNSPSC代码:
12352104
NACRES:
NA.21

质量水平

200

形式

powder

分子量

average mol wt 30,000-70,000

粘度

4-6 cP, 4 % in H2O(20 °C)(lit.)

溶解性

H2O: soluble

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

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应用

聚乙烯醇已被用于：
  • 牛胚胎的体外生产（IVP）
  • 卵母细胞复原和体外成熟
  • 作为基础培养基的大分子成分

生化/生理作用

聚乙烯醇（PVA）是一种多羟基聚合物，可溶于水。已知PVA具有高机械强度和生物相容性，无毒性。因此，它可用作生物医学植入材料。乙酸乙烯酯聚合生成聚乙酸乙烯酯，然后水解形成PVA。它可用于药物递送系统、伤口敷料、透析膜、人造皮肤、外科修复和心血管装置中。

WGK

WGK 1

个人防护装备

Eyeshields, Gloves, type N95 (US)

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分析证书(COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What does "87-90% hydrolyzed" mean?

    Polyvinyl alcohol is normally prepared by hydrolysis of the acetate, CH3(C=O)O, groups of polyvinylacetate, to leave behind the polyvinyl backbone with the OH groups.  The expected degree of acetate hydrolysis is 87-90%.  This means that 87-90% of the side groups are OH, while the remaining 10-13% side groups are CH3(C=O)O.

  6. What does "MALLS" mean on the Specification Sheet or Certificate of Analysis?

    MALLS stands for Multi-Angle Laser Light Scattering.  Sometimes now called Multiangle Light Scattering (MALS), this technique allows for the determination of a MW range and particle size range of a given species in solution.

  7. Can I sterile-filter a solution of this product?

    In general, PVA solutions are very viscous, and sterile-filtering would probably be quite difficult.  It might be better to coat the surface of interest and then irradiate the coated surface under UV light, such as in a cell culture hood.

  8. Can I use this product in cell culture work?

    We have not specifically tested P8136 for use with cultured cells.  This is also not a sterile product. However, several publications claim use of P8136 in culture work.

  9. What is the best way to prepare a solution of Product P8136, poly(vinyl alcohol)?

    Product P8136, poly(vinyl alcohol), should be solubilized in cold water with adequate agitation to ensure complete wetting of the particles. (That is, keep the particles suspended with gentle stirring.) The temperature should then be increased to 85°C for 30 minutes to ensure complete dissolution. Product P8136 has been found to be soluble in water at a concentration of 50 mg/mL, yielding a clear to slightly hazy, colorless to faint yellow solution.

  10. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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Yoshioka K, et al.
Biology of Reproduction, 66(1), 112?119-112?119 (2002)
Structure and applications of poly (vinyl alcohol) hydrogels produced by conventional crosslinking or by freezing/thawing methods
Biopolymers PVA Hydrogels Anionic Polymerisation Nanocomposites, 37-65 (2000)
In Vitro Developmental Competence of In Vitro-Matured Bovine Oocytes Fertilized and Cultured in Completely Defined Media
Keskintepe L and Brackett BG
Biology of Reproduction, 55, 333-339 (1996)
C Wrenzycki et al.
Human reproduction (Oxford, England), 16(5), 893-901 (2001-05-02)
Assisted reproduction technologies have made great progress during the last 15 years in most mammalian species, including humans. Growing evidence indicates that bovine pre-implantation development is a superior model for investigating early human development than the mouse. The purpose of
Nanostructured poly(vinyl alcohol)/bioactive glass and poly(vinyl alcohol)/chitosan/bioactive glass hybrid scaffolds for biomedical applications
Mansur HS and Costa HS
Chemical Engineering Journal, 137, 72-83 (2008)
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