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主要文件

安全信息

C4-BIOC

Sigma-Aldrich

IV型胶原酶,Cls IV

别名:

胶原蛋白A, IV型明胶酶

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1 KIT
CN¥8,017.76

CN¥8,017.76


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1 KIT
CN¥8,017.76

About This Item

UNSPSC代码:
12352204
NACRES:
NA.78

CN¥8,017.76


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表单

powder

质量水平

储存温度

2-8°C

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此商品
SU860098SU860099SU860049
material

clear glass vial, round bottom

material

amber glass vial, round bottom

material

clear glass vial, round bottom

material

clear glass vial, round bottom

fitting

thread for 18

fitting

thread for 18

fitting

thread for 18

fitting

thread for 20 mm

volume

20 mL

volume

20 mL

volume

10 mL

volume

20 mL

compatibility

for use with CTC PAL (Varian, Gerstel, Atas, Shimadzu)

compatibility

for use with CTC PAL (Varian, Gerstel, Atas, Shimadzu)

compatibility

for use with CTC HTC PAL, for use with CTC PAL (Varian, Gerstel, Atas, Shimadzu)

compatibility

for use with PerkinElmer

packaging

pkg of 100 ea

packaging

pkg of 100 ea

packaging

pkg of 100 ea

packaging

pkg of 100 ea

一般描述

IV型胶原酶(Cls IV)属于哺乳动物细胞外中性金属蛋白酶家族成员。消化基底膜的主要组成成分——IV型胶原蛋白。[1]
该产品与Biochrom GmbH部件号C4-22和C4-28相同。由胶原酶、梭菌蛋白酶混合而成的酶,具有胰蛋白酶和蛋白水解活性。推荐用于分离朗格汉斯岛。比活度为每毫克粉末物质125至250 Mandl单位。

应用

IV型胶原酶(Cls IV)用途:
  • 作为杜氏改良Eagle培养基(DMEM)/F12组分,用于消化来自体外受精(IVF)患者的子宮內膜标本[2]
  • 用于胶原酶肝脏灌流法分离大鼠肝细胞[3]
  • 用于分离大鼠肾小球内皮细胞(GEndCs)[4]

法规信息

常规特殊物品
常规特殊物品

  • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    Yaru Huangfu et al.
    Frontiers in pharmacology, 14, 1105726-1105726 (2023-02-07)
    Severe acute pancreatitis (SAP) is a lethal gastrointestinal disorder, yet no specific and effective treatment is available. Its pathogenesis involves inflammatory cascade, oxidative stress, and autophagy dysfunction. Xanthohumol (Xn) displays various medicinal properties, including anti-inflammation, antioxidative, and enhancing autophagic flux.
    Zongliang Zhang et al.
    Journal of translational medicine, 21(1), 23-23 (2023-01-13)
    Chimeric antigen receptor (CAR) T cells and immune checkpoint blockades (ICBs) have made remarkable breakthroughs in cancer treatment, but the efficacy is still limited for solid tumors due to tumor antigen heterogeneity and the tumor immune microenvironment. The restrained treatment
    Weixing Dai et al.
    Cancer communications (London, England), 42(9), 848-867 (2022-07-30)
    Abnormal expression of protein tyrosine phosphatases (PTPs) has been reported to be a crucial cause of cancer. As a member of PTPs, protein tyrosine phosphatase receptor type O (PTPRO) has been revealed to play tumor suppressive roles in several cancers
    Rui-Xian Liu et al.
    iScience, 26(3), 106140-106140 (2023-03-08)
    Antibody-secreting B cells have long been considered the central element of gut homeostasis; however, tumor-associated B cells in human colorectal cancer (CRC) have not been well characterized. Here, we show that the clonotype, phenotype, and immunoglobulin subclasses of tumor-infiltrating B
    Michael Zeisberg et al.
    Biochemical and biophysical research communications, 295(2), 401-407 (2002-08-02)
    Type IV collagen, which is encoded by six genetically distinct alpha-chains (alpha 1-alpha 6), is a major component of the kidney glomerulus. The alpha 1(IV) and alpha 2(IV) chains are present predominantly in the mesangial matrix, whereas the alpha 3(IV)

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