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COO原产地证书/COA分析证书

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BCR265

二苯并[a,e]荧蒽

Name: 二苯并[a,e]荧蒽
Brand: SIAL

BCR^®, certified reference material

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About This Item

经验公式（希尔记法）:

C₂₄H₁₄

CAS号:

5385-75-1

分子量:

302.37

Beilstein:

2120920

MDL编号:

MFCD00215892

UNSPSC代码:

41116107

PubChem化学物质编号:

329773799

NACRES:

NA.24

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Sigma-Aldrich

328774

三(二亚苄基丙酮)二钯(0)

Sigma-Aldrich

177261

DPPF

Sigma-Aldrich

548693

5-氯-2-氟苯甲腈

Sigma-Aldrich

227994

双(二亚苄基丙酮)钯(0)

Sigma-Aldrich

15297

Boc-2-Abz-OH

Sigma-Aldrich

734985

1H-苯并咪唑-2-羧酸

Sigma-Aldrich

228435

5-溴吡啶-3-羧酸

Sigma-Aldrich

I7675

邻碘苯甲酸

Sigma-Aldrich

697230

[1,1′-双(二苯基膦)二茂铁]二氯化钯(II)

Sigma-Aldrich

A89855

邻氨基苯甲酸

等级

certified reference material

Agency

BCR^®

制造商/商品名称

JRC

技术

HPLC: suitable
gas chromatography (GC): suitable

包装形式

neat

储存温度

2-8°C

SMILES字符串

c1ccc-2c(c1)-c3cc4ccccc4c5cc6ccccc6c-2c35

InChI

1S/C24H14/c1-3-9-17-15(7-1)13-22-19-11-5-6-12-20(19)23-18-10-4-2-8-16(18)14-21(17)24(22)23/h1-14H

InChI key

JHOWUOKQHJHGMU-UHFFFAOYSA-N

分析说明

For more information please see:
BCR265

法律信息

BCR is a registered trademark of European Commission

象形图

GHS08

警示用语：

Warning

危险声明

H351

预防措施声明

P201 - P308 + P313

危险分类

Carc. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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分析证书(COA)

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DNA-protein crosslinks induced by exposure of cultured mouse fibroblasts to dibenzo[a,e]fluoranthene and its bay- and pseudo-bay region dihydrodiols.

O Perin-Roussel et al.

Carcinogenesis, 5(3), 379-383 (1984-03-01)

The presence of DNA-protein crosslinks was shown by the alkaline elution technique in cultured mouse fibroblasts treated with dibenzo[a,e]fluoranthene (DBF), a non-alternating carcinogenic PAH. The crosslinks appeared to be between DNA and protein, since the effect disappeared with proteinase treatment.

Differences in metabolic activation of dibenzo[a,e]fluoranthene characterized by 32P-postlabeling in two mouse fibroblast models.

O Périn-Roussel et al.

Cancer letters, 61(3), 207-213 (1992-01-31)

The formation of DNA adducts was investigated in mouse fibroblasts from two different tissues--embryos and adult lung--after incubation with dibenzo[a,e]fluoranthene (DBF) or its major proximate metabolites. The nuclease P1 modification of the 32P-postlabeling method was adapted for detection of DBF-DNA

Multi-step metabolism of the carcinogen dibenzo[a,e]fluoranthene. II. Metabolic pathways.

S Saguem et al.

Carcinogenesis, 4(7), 837-842 (1983-01-01)

The structural identification of nineteen metabolites of dibenzo[a,e]fluoranthene (DBF) obtained by incubation in rat and mouse liver microsomes, allows one to establish a qualitative and semi-quantitative metabolic chart, involving up to three distinct oxidative attacks. The primary steps lead to

Marked differences between mutagenicity in Salmonella and tumour-initiating activities of dibenzo[a,e]fluoranthene proximate metabolites; initiation inhibiting activity of norharman.

F Zajdela et al.

Carcinogenesis, 8(3), 461-464 (1987-03-01)

Dibenzofluoranthene-12,13-dihydrodiol (DBF-12,13-DHD) is six times more mutagenic in Salmonella TA100 than dibenzofluoranthene-3,4-dihydrodiol (DBF-3,4-DHD). However, these two major dibenzo[a,e]fluoranthene (DBF) proximate metabolites, which are immediate precursors of the corresponding diolepoxides, showed on an equimolar basis nearly identical initiation activities on mouse

Metabolic activation of dibenzo(a,e)fluoranthene, a nonalternant carcinogenic polycyclic hydrocarbon, in liver homogenates.

O Perin-Roussel et al.

Cancer research, 40(5), 1742-1749 (1980-05-01)

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二苯并[a,e]荧蒽