推荐产品
方案
≥95%
表单
solid
反应适用性
reaction type: solution phase peptide synthesis
存货情况
available only in USA
储存温度
2-8°C
应用
The in vivo incorporation of clickable unnatural amino acids such as 3-Azido-L-alanine with unique reactivity at a defined postition is used for functionalization of proteins. The azide functionalities in the protein can then be modified with almost any alkyne bearing molecule by Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC). Copper-free alternatives with strained internal alkynes are also available (SPAAC). Some examples enabled with this technique are protein PEGylation, masking with sugars, and the attachment to antibodies.
警示用语：
Danger
危险声明
危险分类
Self-react. C
储存分类代码
5.2 - Organic peroxides and self-reacting hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Kristi L Kiick et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(1), 19-24 (2001-12-26)
The introduction of chemically unique groups into proteins by means of non-natural amino acids has numerous applications in protein engineering and functional studies. One method to achieve this involves the utilization of a non-natural amino acid by the cell's native
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