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About This Item
经验公式（希尔记法）:
C5H7NO2
CAS号:
分子量:
113.11
Beilstein:
2347861
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26
推荐产品
产品名称
L-C-炔丙基甘氨酸, ≥99.0% (TLC)
质量水平
方案
≥99.0% (TLC)
表单
powder
颜色
white
mp
235-239 °C
应用
peptide synthesis
储存温度
2-8°C
SMILES字符串
N[C@@H](CC#C)C(O)=O
InChI
1S/C5H7NO2/c1-2-3-4(6)5(7)8/h1,4H,3,6H2,(H,7,8)/t4-/m0/s1
InChI key
DGYHPLMPMRKMPD-BYPYZUCNSA-N
相关类别
应用
用于 γ-胱硫醚酶不可逆失活的试剂；γ-胱硫醚酶和其他酶的亲和标记试剂；含有该氨基酸的肽可以被氚化至高比放射性
生化/生理作用
L-炔丙基甘氨酸（PAG）是胱硫醚 γ-裂解酶（CSE）的抑制剂，可用于研究硫化氢的合成和生物活性。
L-炔丙基甘酸是一种特异性的 H（2）S 合酶胱硫醚-γ-裂解酶（CSE）的抑制剂，可用于研究 H2S 在生物学过程调节中的作用。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
K Sasaki et al.
Biochemistry international, 10(2), 165-175 (1985-02-01)
Cystathionine accumulated in several tissues of dams and fetuses by a single intraperitoneal administration of L-proparglyglycine to pregnant rats. Cystathionine in the liver of dams reached its maximal level at about 15 hrs after L-proparglyglycine injection (10 mg/300g), while that
A.N. Eberle et al.
Helvetica Chimica Acta, 68, 1880-1880 (1985)
Shiau Wei Lee et al.
Glia, 54(2), 116-124 (2006-05-24)
Hydrogen sulphide (H2S), which is produced endogenously from L-cysteine in mammalian tissues, has been suggested to function as a neuromodulator in the brain. However, the role of H2S in microglial cells is unclear. In this study, the effect of exogenous
Mechanism of inactivation of gamma-cystathionase by the acetylenic substrate analogue propargylglycine.
W Washtien et al.
Biochemistry, 16(11), 2485-2491 (1977-05-31)
Metabolic consequences of affinity labeling of cystathionase and alanine aminotransferase by L-propargylglycine in vivo.
S Shinozuka et al.
European journal of biochemistry, 124(2), 377-382 (1982-05-17)
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