81838
L-C-炔丙基甘氨酸
≥99.0% (TLC)
别名:
L-炔丙基甘氨酸, (S)-2-氨基-4-戊炔酸
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关于此项目
经验公式（希尔记法）:
C5H7NO2
化学文摘社编号:
分子量:
113.11
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
Beilstein/REAXYS Number:
2347861
MDL number:
产品名称
L-C-炔丙基甘氨酸, ≥99.0% (TLC)
SMILES string
N[C@@H](CC#C)C(O)=O
InChI
1S/C5H7NO2/c1-2-3-4(6)5(7)8/h1,4H,3,6H2,(H,7,8)/t4-/m0/s1
InChI key
DGYHPLMPMRKMPD-BYPYZUCNSA-N
assay
≥99.0% (TLC)
form
powder
color
white
mp
235-239 °C
application(s)
peptide synthesis
storage temp.
2-8°C
Quality Level
Application
用于 γ-胱硫醚酶不可逆失活的试剂；γ-胱硫醚酶和其他酶的亲和标记试剂；含有该氨基酸的肽可以被氚化至高比放射性
Biochem/physiol Actions
L-炔丙基甘氨酸（PAG）是胱硫醚 γ-裂解酶（CSE）的抑制剂，可用于研究硫化氢的合成和生物活性。
L-炔丙基甘酸是一种特异性的 H（2）S 合酶胱硫醚-γ-裂解酶（CSE）的抑制剂，可用于研究 H2S 在生物学过程调节中的作用。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
K Sasaki et al.
Biochemistry international, 10(2), 165-175 (1985-02-01)
Cystathionine accumulated in several tissues of dams and fetuses by a single intraperitoneal administration of L-proparglyglycine to pregnant rats. Cystathionine in the liver of dams reached its maximal level at about 15 hrs after L-proparglyglycine injection (10 mg/300g), while that
Bridget Fox et al.
Journal of cellular and molecular medicine, 16(4), 896-910 (2011-06-18)
Hydrogen sulfide (H(2)S) has recently been proposed as an endogenous mediator of inflammation and is present in human synovial fluid. This study determined whether primary human articular chondrocytes (HACs) and mesenchymal progenitor cells (MPCs) could synthesize H(2)S in response to
Mechanism of inactivation of gamma-cystathionase by the acetylenic substrate analogue propargylglycine.
W Washtien et al.
Biochemistry, 16(11), 2485-2491 (1977-05-31)
Metabolic consequences of affinity labeling of cystathionase and alanine aminotransferase by L-propargylglycine in vivo.
S Shinozuka et al.
European journal of biochemistry, 124(2), 377-382 (1982-05-17)
A.N. Eberle et al.
Helvetica Chimica Acta, 68, 1880-1880 (1985)
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