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Merck
CN

158127

Sigma-Aldrich

多聚甲醛

powder, 95%

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别名:
聚氧亚甲基
线性分子式:
HO(CH2O)nH
CAS号:
分子量:
30.03 (as monomer)
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.21

蒸汽密度

1.03 (vs air)

质量水平

蒸汽压

<1.45 mmHg ( 25 °C)

检测方案

95%

形式

powder

自燃温度

572 °F

expl. lim.

73 %

mp

120-170 °C (lit.)

密度

0.88 g/mL at 25 °C (lit.)

储存温度

2-8°C

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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一般描述

多聚甲醛又称聚甲醛。其作为外部CO源参与芳香醛和酯的合成。

警示用语:

Danger

危险分类

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Flam. Sol. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the difference between formaldehyde and paraformaldehyde?

    Paraformaldehyde is the polymeric form of formaldehyde. It is a solid. Formaldehyde is a gas which when dissolved in water gives a formaldehyde solution. Commercially available formaldehyde solutions usually contain 10-15% methanol, which prevents the formaldehyde from forming the polymeric paraformaldehyde.

  4. How does Product 158127, Paraformaldehyde, compare to prilled paraformaldehyde?

    Prilled has the appearance of small white beads.  Product 158127 is a powder, not prilled.

  5. Do you have a recommended method for preparing solutions of Paraformaldehyde, Product 158127?

    Paraformaldehyde does not dissolve but rather can be depolymerized in solution. Depolymerized solutions can be prepared in water with heating to 55-60°C. If necessary, further addition of 1-2 drops of a sodium hydroxide solution may be required. Some protocols suggest that paraformaldehyde should be prepared in buffered solutions such as phosphate buffer or PBS at approximately pH 7.

  6. How stable are solutions of Product 158127, Paraformaldehyde?

    Buffered solutions of 2-4% formaldehyde may be used for up to two weeks if stored in brown bottles at 2-8°C.

  7. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  8. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  9. What are the differences between the Paraformaldheyde products and which is best suited for use as a fixative for Electron Microscopy?

    Product 16005 is sold only in Europe and is not available to US customers.The primary differences among the various products is in the form for each product.  P6148 is listed as crystalline, 158127 is listed as powder, and 441244 is listed as prilled. The product information page for 441244 states the prilled form will go into solution more readily, but the prilled, crystalline, and powder forms are equivalent in terms on use. The prilled form is expected to slow down the rate of sublimation compared to the powder or the crystalline forms.  Any of the 3 products should be suitable for use as a fixative.  However, once prepared, paraformaldehyde solutions are unstable unless methanol is added as a stabilizer. Customer options vary from preparing solutions daily to storing solutions for 2 or 3 weeks. If used as a fixative for electron microscopy, we recommend preparing solutions fresh daily to avoid the risk of repeating tedious EM work due to deterioration of the fixative.  For less critical applications, it would be more acceptable to use solutions stored for longer periods of time.

  10. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expression following kainate-induced seizures in rats
Sun J, et al.
International Journal of Molecular Medicine, 30(4), 739-746 (2012)
Cytometry, 256-256 (2000)
L L Lanier et al.
Journal of immunological methods, 47(1), 25-30 (1981-01-01)
The objective of this study was to find a simple method to preserve cells for subsequent flow cytometry (FACS) analysis. We determined that fixation in 1% paraformaldehyde-0.85% saline solution did not significantly alter the Coulter volume, light scatter of fluorescence
Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron microscopy.
I W McLean et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 22(12), 1077-1083 (1974-12-01)
Morphological and physiological species-dependent characteristics of the rodent Grueneberg ganglion
Brechbuhl J, et al.
Frontiers in Neuroanatomy, 8, 87-87 (2014)

实验方案

本协议描述了一种使用甲醛完成化学交联蛋白质的方法。除零长交联剂外,甲醛是交联跨度最短(~2-3 Å)的交联剂,因此使其成为非常可靠地检测特定蛋白质-蛋白质相互作用的理想工具。

Formaldehyde cross-linking protocol detects specific protein interactions with confidence.

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