推荐产品
生物来源
mouse
偶联物
ALEXA FLUOR™ 488
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
1A6, monoclonal
种属反应性
vertebrates
制造商/商品名称
Upstate®
技术
flow cytometry: suitable
western blot: suitable
同位素/亚型
IgG2bκ
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... NOS1(4842)
应用
This Anti-Nitrotyrosine Antibody, clone 1A6, Alexa Fluor 488 conjugate is validated for use in FC, WB for the detection of Nitrotyrosine.
质量
Routinely evaluated by immunoblot.
外形
Protein G Purified mouse monoclonal in a solution of 1% BSA, PBS, 0.05% Tween, and 0.05% sodium azide as a preservative.
储存及稳定性
Stable for 1 year at 2–8°C from date of shipment in undiluted aliquots. Upon receipt, and prior to removing the cap, centrifuge the vial to remove any material in the cap. DO NOT FREEZE. Store at 2–8°C in aliquots, in the dark. Avoid repeated warming/cooling cycles.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Biological selectivity and functional aspects of protein tyrosine nitration.
Ischiropoulos, Harry
Biochemical and biophysical research communications, 305, 776-783 (2003)
Relevance of protein nitration in brain injury: a key pathophysiological mechanism in neurodegenerative, autoimmune, or inflammatory CNS diseases and stroke.
Sarchielli, P, et al.
Amino Acids, 25, 427-436 (2003)
Compartmentalized nitrosation and nitration in mitochondria.
Ghafourifar, Pedram and Colton, Carol A
Antioxidants & Redox Signaling, 5, 349-354 (2003)
J Torreilles et al.
BMC immunology, 2, 1-1 (2001-03-07)
Peroxynitrite is increasingly proposed as a contributor to defence system in marine bivalve. It can be formed by combination of superoxide and nitric oxide, and can react with tyrosine residues of proteins giving rise to 3-nitrotyrosine. The present article describes
C Ayata et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 17(18), 6908-6917 (1997-09-15)
We investigated the role of neuronal (type I) nitric oxide synthase (nNOS) in NMDA-mediated excitotoxicity in wild-type (SV129 and C57BL/6J) and type I NOS knock-out (nNOS-/-) mice and examined its relationship to apoptosis. Excitotoxic lesions were produced by intrastriatal stereotactic
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