1.06432
二水合柠檬酸三钠
crystalline, EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, USP, E 331
别名:
柠檬酸钠三盐基 二水合物, 柠檬酸 三钠盐 二水合物, 柠檬酸三钠 二水合物
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线性分子式:
HOC(COONa)(CH2COONa)2 · 2H2O
化学文摘社编号:
分子量:
294.10
UNSPSC Code:
12352107
EC Index Number:
200-675-3
E Number:
E331
MDL number:
Beilstein/REAXYS Number:
6104939
产品名称
二水合柠檬酸三钠, crystalline, EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, USP, E 331
InChI
1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3
SMILES string
O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O
InChI key
NLJMYIDDQXHKNR-UHFFFAOYSA-K
agency
BP
JP
Ph. Eur.
USP
product line
EMPROVE® ESSENTIAL
form
crystalline
solid
pH
7.5-9.0 (25 °C, 50 g/L in H2O)
pKa
(1) 3.1, (2) 4.8, (3) 6.4
mp
150 °C (anhydrous substance)
>300 °C (lit.)
application(s)
liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation
storage temp.
2-30°C
Quality Level
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Application
tri-Sodium citrate dihydrate is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.
General description
Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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