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1.06447

二水合柠檬酸三钠

EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP, ACS, E 331

别名:

柠檬酸钠三盐基 二水合物, 柠檬酸 三钠盐 二水合物, 柠檬酸三钠 二水合物

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关于此项目

线性分子式:
HOC(COONa)(CH2COONa)2 · 2H2O
化学文摘社编号:
6132-04-3
分子量:
294.10
UNSPSC Code:
12352107
EC Index Number:
200-675-3
E Number:
E331
MDL number:
MFCD00150031
Beilstein/REAXYS Number:
6104939
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Quality Level

500

agency

BP, ChP, JP, Ph. Eur., USP, suitable for SM 4500 - NH3

product line

EMPROVE® EXPERT

form

solid

feature

RNase and DNase free

impurities

endotoxins, low

pH

7.5-9.0 (25 °C, 50 g/L in H2O)

pKa 

(1) 3.1, (2) 4.8, (3) 6.4

mp

150 °C (anhydrous substance), >300 °C (lit.)

application(s)

liquid formulation
ophthalmics
parenterals
pharma/biopharma processes
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-30°C

SMILES string

O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3

InChI key

NLJMYIDDQXHKNR-UHFFFAOYSA-K

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

tri-Sodium citrate dihydrate is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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全球贸易项目编号

货号GTIN
106447100004022536076928
106447500004022536076942
106447000104027269279790
106447902904022536940328
106447905104065272192576
106447901204065270749765