推荐产品
方案
99%
沸点
325-330 °C (lit.)
mp
118-120 °C (lit.)
SMILES字符串
C1CCc2c(C1)[nH]c3ccccc23
InChI
1S/C12H13N/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1,3,5,7,13H,2,4,6,8H2
InChI key
XKLNOVWDVMWTOB-UHFFFAOYSA-N
应用
1,2,3,4-四氢咔唑可作为起始材料：
- 通过光氧化反应制备螺[环戊烷-1,2′-吲哚啉-3′-酮]。
- 通过N-酰基化反应制备9-酰基-1,2,3,4-四氢咔唑。
- 通过钯催化的不对称加氢反应制备咔唑。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
Photooxygenation of 1, 2, 3, 4-Tetrahydrocarbazole: Synthesis of Spiro [cyclopentane-1, 2 `-indolin-3 `-one]
Mateo CA, et al.
The Journal of Organic Chemistry, 61(2), 810-812 (1996)
Pd-catalyzed asymmetric hydrogenation of unprotected indoles activated by bronsted acids
Wang D-S, et al.
Journal of the American Chemical Society, 132(26), 8909-8911 (2010)
Jing Chen et al.
Archiv der Pharmazie, 342(3), 165-172 (2009-02-13)
A novel series of 2-substituted aminomethyl-9-alkyl-1,2,3,4-tetrahydrocarbazole-1-ones 5a-q was synthesized via aminomethylation of 9-alkyl-1,2,3,4-tetrahydrocarbazole-1-ones 4a-e with hydrochlorides of the respective amines 6a-m. The structures of these newly synthesized compounds were characterized by (1)H-NMR, MS, and elemental analysis. All the compounds were
Romano Di Fabio et al.
Bioorganic & medicinal chemistry letters, 16(6), 1749-1752 (2005-12-21)
The SAR of a new series of tetrahydrocarbazole derivatives is described: the appropriate decoration of this template led to the identification of a new class of NPY-1 antagonists showing good in vitro potency and a promising in vivo pharmacokinetic profile
Subhasish Neogi et al.
Journal of combinatorial chemistry, 12(5), 617-629 (2010-07-01)
The one-pot synthesis of a new substituted 1,2,3,4-tetrahydrocarbazoles has been described via Petasis reactions. These tetrahydrocarbazoles exhibits various medicinal importance and might be suitable for elaboration into larger peptides at carboxy termini. The scope and limitations of this method have
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