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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
CN
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主要文件

安全信息

Q0750

Sigma-Aldrich

奎尼丁 盐酸盐 一水合物

technical grade

别名:

6′-Methoxycinchonan-9-ol hydrochloride monohydrate

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5 G
¥363.28

¥363.28


预计发货时间2025年6月20日详情


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5 G
¥363.28

About This Item

经验公式(希尔记法):
C20H24N2O2 · HCl · H2O
CAS号:
分子量:
378.89
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

¥363.28


预计发货时间2025年6月20日详情


获取大包装报价

等级

technical grade

杂质

≤20% Dihydroquinidine (according to USP specifications., actual content given on label)

SMILES字符串

O.Cl.[H][C@@]1(C[C@@H]2CC[N@H]1C[C@@H]2C=C)[C@@H](O)c3ccnc4ccc(OC)cc34

InChI

1S/C20H24N2O2.ClH.H2O/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H;1H2/t13-,14-,19+,20-;;/m0../s1

InChI key

SGVZDMWHXVXUBY-KAIFKDDSSA-N

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2263222630PHL80965
grade

technical grade

grade

-

grade

-

grade

primary reference standard

impurities

≤20% Dihydroquinidine (according to USP specifications., actual content given on label)

impurities

-

impurities

≤10% dihydroquinine hydrochloride (HPLC)

impurities

-

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Gene Information

-

Gene Information

-

Gene Information

-

应用

Studied for pharmacological activity causing energy shifts from mitochondrial respiration to glycolysis

生化/生理作用

IA 类抗心律失常药;钾通道阻断剂。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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    European journal of drug metabolism and pharmacokinetics, 41(6), 819-824 (2015-12-03)
    We have recently found an H We investigated the uptake and efflux of quinidine in MDCK cells. The uptake of 100 µM quinidine into MDCK cells was decreased by acidification of extracellular pH or alkalization of intracellular pH. In addition, the
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    Journal of medical virology, 91(7), 1182-1190 (2019-02-26)
    Studies aimed at repurposing existing drugs revealed that some antimalarial compounds possess anti-Zika virus (anti-ZIKV) activity. Here, we further tested 14 additional antimalarial drugs and their metabolites or analogs for anti-ZIKV activity using a phenotypic screening approach. We identified four

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