跳转至内容
Merck
CN
所有图片(3)

文件

安全信息

Q0750

Sigma-Aldrich

奎尼丁 盐酸盐 一水合物

technical grade

别名:

6′-Methoxycinchonan-9-ol hydrochloride monohydrate

登录查看公司和协议定价
所有图片(3)

About This Item

经验公式（希尔记法）:
C20H24N2O2 · HCl · H2O
CAS号:
6151-40-2
分子量:
378.89
EC 号:
205-001-1
MDL编号:
MFCD00198101
UNSPSC代码:
12352100
PubChem化学物质编号:
57654579
NACRES:
NA.22

等级

technical grade

质量水平

200

杂质

≤20% Dihydroquinidine (according to USP specifications., actual content given on label)

SMILES字符串

O.Cl.[H][C@@]1(C[C@@H]2CC[N@H]1C[C@@H]2C=C)[C@@H](O)c3ccnc4ccc(OC)cc34

InChI

1S/C20H24N2O2.ClH.H2O/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H;1H2/t13-,14-,19+,20-;;/m0../s1

InChI key

SGVZDMWHXVXUBY-KAIFKDDSSA-N

基因信息

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

相关类别

应用

Studied for pharmacological activity causing energy shifts from mitochondrial respiration to glycolysis

生化/生理作用

IA 类抗心律失常药；钾通道阻断剂。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302 + H312 + H332

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Miki Fukao et al.
European journal of drug metabolism and pharmacokinetics, 41(6), 819-824 (2015-12-03)
We have recently found an H We investigated the uptake and efflux of quinidine in MDCK cells. The uptake of 100 µM quinidine into MDCK cells was decreased by acidification of extracellular pH or alkalization of intracellular pH. In addition, the
Keisuke Oda et al.
The Journal of pharmacy and pharmacology, 69(12), 1736-1744 (2017-10-06)
Possible interaction of green tea beverage (GT) containing cyclodextrins and high concentration catechins, a drinking water, with P-glycoprotein (P-gp) substrates was examined in vitro and in vivo. Effects of GT on the uptake of rhodamine 123 by LLC-GA5-COL150 cells and intestinal efflux
Faisal E Al Jofi et al.
Cytotherapy, 20(5), 650-659 (2018-03-21)
Compelling evidence indicates that metformin, a low-cost and safe orally administered biguanide prescribed to millions of type 2 diabetics worldwide, induces the osteoblastic differentiation of mesenchymal stromal cells (MSCs) through the 5' adenosine monophosphate (AMP)-activated protein kinase (AMPK) pathway. As
Rajesh Chavan et al.
Xenobiotica; the fate of foreign compounds in biological systems, 51(3), 251-261 (2020-10-21)
Nafithromycin is a next generation lactone ketolide antibiotic slated to enter phase III clinical development in India for the treatment of CABP as a shorter 800 mg-OD X3 day therapeutic regimen. Nafithromycin exhibits potent activity against MDR Streptococcus pneumoniae including erythromycin and
Yingshan Han et al.
Journal of medical virology, 91(7), 1182-1190 (2019-02-26)
Studies aimed at repurposing existing drugs revealed that some antimalarial compounds possess anti-Zika virus (anti-ZIKV) activity. Here, we further tested 14 additional antimalarial drugs and their metabolites or analogs for anti-ZIKV activity using a phenotypic screening approach. We identified four
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门