一般描述
Hyaluronic acid (HA) is a a natural polymer found in many extracellular matrices (ECM). Its biocompatibility, biodegradability, and biomimetic chacteristics make it one of the most advantagous biopolymers for myriad of biomedical applications including drug delivery, tissue engineering, hydrogel development, cosmetics, regenerative medicine and 3D bioprinting.
Unlike other HA products which are typically available in a sodium salt form, HA acid form is soluble in organic solvents such as DMSO. This allows for a larger range of possible chemical modifications and functionalization. For instance, the carboxylic acid of the glucoronic acid can be modified or functionalized with hydrazine end groups.
Unlike other HA products which are typically available in a sodium salt form, HA acid form is soluble in organic solvents such as DMSO. This allows for a larger range of possible chemical modifications and functionalization. For instance, the carboxylic acid of the glucoronic acid can be modified or functionalized with hydrazine end groups.
应用
- Tissue engineering including cartilage tissue engineering, bone tissue engineering, and other musculoskeletal tissues
- Drug delivery and a carrier of small molecules, large molecules, and biomolecules
- Biosensors, films and transdermal microneedles development
- Medical device coatings, wound healing, and cosmetics
特点和优势
- The same advantages of HA but in acid form
- Soluble in organic solvents such as DMSO
- Larger range of chemical modifications and functionalization possibilities
相关产品
产品编号
说明
价格
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
A mild and straightforward one-pot hyaluronic acid functionalization through termination of poly-(2-alkyl-2-oxazoline)
Madau M, et al.
Polymer, 230, 124059-124059 (2021)
Thiolated Hyaluronic Acid as Versatile Mucoadhesive Polymer: From the Chemistry Behind to Product Developments-What Are the Capabilities?
Griesser J, et al.
Polymers (Basel, Switzerland), 28, 243-243 (2018)
Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory
Gupta R C, et al.
Frontiers in veterinary science, 25, 192-192 (2019)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门