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Merck
CN

924474

Sigma-Aldrich

透明质酸

Low Viscosity, Low endotoxin

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别名:
3D 生物打印, HA, 玻尿酸
UNSPSC代码:
12352201
NACRES:
NA.23

质量水平

形式

(powder or chunk(s) or fibers)

杂质

<10 CFU/g Bioburden
<100 EU/g Endotoxin

颜色

white to off-white

适用性

conforms to structure for NMR

储存温度

2-8°C

一般描述

透明质酸(HA)是细胞外基质中由交替相间的D-葡萄糖醛酸和N-乙酰-D-氨基葡萄糖聚合而成的线性多糖。HA常用于化学改性制备共价交联的水凝胶。HA还可用于细胞表面受体CD44和RHAMM识别以及透明质酸酶催化降解。

应用

透明质酸在下列生物医药中的应用日渐增加:
  • 细胞迁移
  • 血管生成
  • 细胞活力
  • 细胞增殖

我们的低内毒素透明质酸同时经过内毒素(< 100 Eu/g)和微生物负荷(< 10 CFU/g)水平测试,方便用户选择适合的研究材料。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Federica Camin et al.
Journal of agricultural and food chemistry, 58(1), 570-577 (2009-12-17)
H, C, and O stable isotope ratios and the elemental profile of 267 olive oils and 314 surface waters collected from 8 European sites are presented and discussed. The aim of the study was to investigate if olive oils produced
Xian Xu et al.
Soft matter, 8(12), 3280-3294 (2012-03-16)
Hyaluronic acid (HA) is one of nature's most versatile and fascinating macromolecules. Being an essential component of the natural extracellular matrix (ECM), HA plays an important role in a variety of biological processes. Inherently biocompatible, biodegradable and non-immunogenic, HA is
Tracey J Brown
Current pharmaceutical biotechnology, 9(4), 253-260 (2008-08-12)
Despite advances in chemotherapeutic regimens, the treatment of metastatic cancer remains a challenge. A key problem with chemotherapy drugs is nonspecific drug distribution, resulting in low tumor concentrations and systemic toxicity. The holy grail of clinical cancer research has been
Kevin T Dicker et al.
Acta biomaterialia, 10(4), 1558-1570 (2013-12-24)
Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid and N-acetyl-d-glucosamine. It is evolutionarily conserved and abundantly expressed in the extracellular matrix (ECM), on the cell surface and even inside cells. Being a simple polysaccharide, HA exhibits
Jason A Burdick et al.
Advanced materials (Deerfield Beach, Fla.), 23(12), H41-H56 (2011-03-12)
Hyaluronic acid (HA), an immunoneutral polysaccharide that is ubiquitous in the human body, is crucial for many cellular and tissue functions and has been in clinical use for over thirty years. When chemically modified, HA can be transformed into many

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