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Merck
CN

911690

Sigma-Aldrich

C5 Lenalidomide

≥95%

别名:

3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione, E3 ligase ligand, Ligand for PROTAC® research

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About This Item

经验公式(希尔记法):
C13H13N3O3
分子量:
259.26
MDL编号:
UNSPSC代码:
12352101
NACRES:
NA.22

ligand

C5 Lenalidomide

质量水平

检测方案

≥95%

形式

powder

反应适用性

reagent type: ligand

储存温度

2-8°C

SMILES字符串

NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1

应用

C5 Lenalidomide is a derivative of the Cereblon (CRBN)-binding ligand lenalidomide, which possesses an amine at the C4 position. C5 Lenalidomide can be used to bind the CRBN E3 ubiquitin ligase in targeted protein degradation research or in the synthesis of protein degraders with a C5 exit vector. Learn more about proteolysis-targeting chimeras (PROTACs) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

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说明
价格

象形图

Health hazard

警示用语:

Warning

危险声明

危险分类

Repr. 2 - STOT RE 2

靶器官

Blood

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Protein Degrader Building Blocks are a collection of crosslinker-E3 ligand conjugates with a pendant functional group for covalent linkage to a target ligand.

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