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Merck
CN

363081

Sigma-Aldrich

聚乙烯醇

average Mw 85,000-124,000, 87-89% hydrolyzed

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About This Item

线性分子式:
[-CH2CHOH-]n
CAS号:
MDL编号:
UNSPSC代码:
12352104
NACRES:
NA.23

质量水平

形式

powder or crystals

分子量

average Mw 85,000-124,000

落球

23-27 cP, 4 % in H2O(20 °C)(lit.)

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

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相关类别

一般描述

聚乙烯醇(PVA)是一种线性 亲水性合成聚合物,其主链仅由碳原子组成。 由于其惰性和稳定性,它被认为是安全和生物相容的。 它在厌氧和好氧条件下都是可生物降解的。由于 其独特的粘附性、安全性、强度、 成膜性、溶胀性和非致癌性等特性,它被广泛应用于 纸张、粘合剂、食品、生物医学和制药行业。部分水解的 PVA(87–89%)更易溶于水,并且对疏水表面具有更大的柔韧性和粘附性。

应用

PVA 对于 用于药物递送系统的聚合物具有显著的性能,例如高 表面稳定性和低蛋白质吸附。PVA 用在固体 分散体中防止晶体形成并提高药物溶解度。 它也可以用作造粒液,以防止晶体生长和 成核缓慢。与它的共聚物一起,它可以用于 亲水性和疏水性药物。 PVA 水凝胶和 微粒可用于癌症药物的药物输送系统。

PVA 可作为 表面稳定剂用于制备四环素缓释药物递送 载体。

高浓度藻酸盐/聚乙烯醇 (PVA)生物墨水可用于制备 3D 生物打印多孔支架。PVA 溶胶 从印刷支架的部分扩散产生了大量的于大量样品的并行测试。 微孔。

PVA 也可以作为水溶性聚合物模板, 通过原位聚合合成纳米聚吡咯。PVA 在水中产生稳定的聚吡咯纳米球分散体,纳米球的大小 取决于 PVA 的分子量和浓度。

WGK

WGK 1

闪点(°F)

No data available

闪点(°C)

No data available

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Recent progress in whole genome sequencing has revealed that animals have various kinds of opsin genes for photoreception. Among them, most opsin genes have introns in their coding regions. However, it has been known for a long time that teleost
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International journal of pharmaceutics, 600, 120478-120478 (2021-03-17)
Polyvinyl alcohol (PVA) is a biodegradable semicrystalline synthetic polymer that has been used for biomedical applications for several years. In the pharmaceutical area, PVA has been widely used to prepare solid dispersions to improve the solubility of drugs. Furthermore, it
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PloS one, 6(11), e27605-e27605 (2011-11-24)
Mucosal vaccination has been demonstrated to be an effective means of eliciting protective immunity against aerosol infections of foot and mouth disease virus (FMDV) and various approaches have been used to improve mucosal response to this pathogen. In this study
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Multipotent self-renewing haematopoietic stem cells (HSCs) regenerate the adult blood system after transplantation1, which is a curative therapy for numerous diseases including immunodeficiencies and leukaemias2. Although substantial effort has been applied to identifying HSC maintenance factors through the characterization of
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The journal of physical chemistry. B, 117(10), 2947-2954 (2013-02-15)
A stretched poly(vinyl alcohol) (PVA) film provides a unique matrix that enables also short DNA oligonucleotide duplex to be oriented and studied by linear dichroism (LD). This matrix further allows controlling DNA secondary structure by proper hydration (A or B

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