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Merck
CN

253324

Sigma-Aldrich

3-羧基-2,2,5,5-四甲基吡咯烷1-氧

98%

别名:

3-(羧基)-2,2,5,5-四甲基-1-吡咯烷基氧基, 3-羧基-2,2,5,5-四甲基-1-吡咯烷基氧自由基

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About This Item

经验公式(希尔记法):
C9H16NO3
CAS号:
分子量:
186.23
EC 号:
MDL编号:
UNSPSC代码:
12352000
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

98%

mp

200 °C (dec.) (lit.)

储存温度

2-8°C

SMILES字符串

CC1(C)CC(C(O)=O)C(C)(C)N1[O]

InChI

1S/C9H16NO3/c1-8(2)5-6(7(11)12)9(3,4)10(8)13/h6H,5H2,1-4H3,(H,11,12)

InChI key

GEPIUTWNBHBHIO-UHFFFAOYSA-N

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应用

用于制备含硝酰自由基的四苯基卟啉。
自旋标记物,已用于研究种子和花粉的分子迁移和长期稳定性。可与寡聚核苷酸共价结合,制备对电子自旋共振敏感的 DNA 探针。乙酰氧基甲酯是酯酶敏感探针,可越过血脑屏障用于电子自旋共振-计算断层成像。
自旋标记物。其阴离子形式已用于测定中性增溶质在阴离子胶束中的分配系数。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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M Alecci et al.
Physics in medicine and biology, 43(7), 1899-1905 (1998-08-14)
The use of RF (100 to 300 MHz) PEDRI and CW-EPR techniques allows the in vivo study of large animals such as whole rats and rabbits. Recently a PEDRI instrument was modified to also allow CW-EPR spectroscopy with samples of
K Mäder et al.
Pharmaceutical research, 14(6), 820-826 (1997-06-01)
The purpose of this study was to compare drug release and polymer erosion from biodegradable P(FAD-SA) polyanhydrides in vitro and in vivo in real time and with minimal disturbance of the investigated system. P(FAD-SA) 20:80 and P(FAD-SA) 50:50 polymer tablets
S Zöllner et al.
The Journal of biological chemistry, 272(37), 23076-23080 (1997-09-12)
Nitroxides are known to exert superoxide dismutase-mimetic properties and to decrease O-2- and H2O2-mediated cytotoxicity. However, the effect of nitroxides on .NO homeostasis has not been studied yet. The present study investigates the effect of nitroxides on the detectable amount
M Alecci et al.
Biophysical journal, 67(3), 1274-1279 (1994-09-01)
A radio frequency (RF) (280 MHz) electron paramagnetic resonance (EPR) spectroscopy and imaging apparatus has been used to localize a pyrrolidine nitroxide free radical in the rat abdomen and thorax. The nitroxide 2,2.5.5,-tetramethylpyrrolidine-1-oxyl-3- carboxylic acid (PCA) had a whole body
Guo-Xing Zhang et al.
Hypertension (Dallas, Tex. : 1979), 43(1), 117-124 (2003-11-26)
The relations among hypertensive response, oxidative stress, and mitogen-activated protein kinase (MAPK) in cardiovascular tissues have not been fully established. We investigated the involvement of reactive oxygen species on changes in the hemodynamics and cardiovascular MAPKs activities induced by acutely

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