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Merck
CN

C5151

Sigma-Aldrich

3-氨基甲酰-PROXYL

别名:

3-氨基甲酰-2,2,5,5-四甲基-1-吡咯烷氧基, 3-氨基甲酰-2,2,5,5-四甲基四氢吡咯氮氧自由基

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About This Item

经验公式(希尔记法):
C9H17N2O2
CAS号:
分子量:
185.24
EC 号:
MDL编号:
UNSPSC代码:
12352000
PubChem化学物质编号:
NACRES:
NA.22

表单

powder

质量水平

mp

173-175 °C (lit.)

储存温度

2-8°C

SMILES字符串

CC1(C)CC(C(N)=O)C(C)(C)N1[O]

InChI

1S/C9H17N2O2/c1-8(2)5-6(7(10)12)9(3,4)11(8)13/h6H,5H2,1-4H3,(H2,10,12)

InChI key

XNNPAWRINYCIHL-UHFFFAOYSA-N

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应用

自旋标记物,用于通过电子自旋共振成像进行自由基的体内无创检测。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Ken-Ichiro Matsumoto et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 12(8), 2455-2462 (2006-04-28)
There is considerable research directed toward the identification and development of functional contrast agents for medical imaging that superimpose tissue biochemical/molecular information with anatomical structures. Nitroxide radicals were identified as in vivo radioprotectors. Being paramagnetic, they can provide image contrast
Tomiko Mikuni et al.
Cancer research, 64(18), 6495-6502 (2004-09-18)
Electron paramagnetic resonance imaging (EPRI) enables noninvasive spatial mapping of free radical metabolism and has recently been shown to provide in vivo physiologic information regarding alterations in the redox state of tumors and neoplastic tissues. With the use of nitroxide
Th Herrling et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 63(4), 840-845 (2006-03-18)
Free radicals/reactive oxygen species (ROS) generated in skin by UV irradiation were measured by electron spin resonance (ESR). To increase the sensitivity of measurement the short life free radicals/ROS were scavenged and accumulated by using the nitroxyl probe 3-carboxy-2,2,5,5-tetrametylpyrrolidine-1-oxyl (PCA).
Guohan Hu et al.
Journal of neurosurgery, 98(2), 393-396 (2003-02-21)
Nitroxides mimic superoxide dismutase (SOD) biochemically and may prevent free radical oxidative injury in settings in which endogenous SOD is overwhelmed. The authors have previously shown the efficacy of a nitroxide, Tempol, in reducing stroke infarct size. Of the nitroxides
T Herrling et al.
Free radical biology & medicine, 35(1), 59-67 (2003-06-27)
Reactive free radicals and reactive oxygen species (ROS) induced by ultraviolet irradiation in human skin are strongly involved in the occurrence of skin damages like aging and cancer. In the present work an ex vivo method for the detection of

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