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202487

Sigma-Aldrich

聚乙二醇甲基醚

average MN 550, methoxy, hydroxyl

别名:

mPEG, 甲氧基聚乙二醇, 聚乙二醇单甲醚

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About This Item

线性分子式:
CH3(OCH2CH2)nOH
CAS号:
9004-74-4
MDL编号:
MFCD00084416
UNSPSC代码:
12162002
PubChem化学物质编号:
24852066
NACRES:
NA.23

产品名称

聚乙二醇甲基醚, average Mn 550

蒸汽密度

>1 (vs air)

质量水平

200

蒸汽压

0.05 mmHg ( 20 °C)

表单

semisolid

分子量

average Mn 550

折射率

n20/D 1.455

粘度

7.5 cSt(210 °F)(lit.)

转变温度

Tm 20 °C

密度

1.089 g/mL at 25 °C

Ω端

hydroxyl

α端

methoxy

SMILES字符串

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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应用

聚（乙二醇）甲基醚可作为成孔剂， 以制备亲水性增强的聚砜膜。

聚（乙二醇）甲基醚接枝的聚酰胺 （PAMAM）树枝状聚合物可作为抗癌药物的 载药体系。

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

359.6 °F - closed cup

闪点(°C)

182 °C - closed cup

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000377733
0000319951
0000319951
0000377733
0000249498

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Jiani Zheng et al.
Langmuir : the ACS journal of surfaces and colloids, 28(37), 13261-13273 (2012-08-28)
Alginate/chitosan/alginate (ACA) hydrogel microcapsules were modified with methoxy poly(ethylene glycol) (MPEG) to improve protein repellency and biocompatibility. Increased MPEG surface graft density (n(S)) on hydrogel microcapsules was achieved by controlling the grafting parameters including the buffer layer substrate, membrane thickness
Lei Liu et al.
International journal of pharmaceutics, 443(1-2), 175-182 (2013-01-05)
This work aims to develop curcumin (Cur) loaded biodegradable self-assembled polymeric micelles (Cur-M) to overcome poor water solubility of Cur and to meet the requirement of intravenous administration. Cur-M were prepared by solid dispersion method, which was simple and easy
Yiyi Yu et al.
Journal of pharmaceutical sciences, 102(3), 1054-1062 (2013-01-03)
To promote the application of methoxy poly(ethylene glycol)-cholesterol (mPEG-Chol), mPEG-Chol was used to prepare core-shell micelles encapsulating poorly water-soluble docetaxel (DTX-PM) by modified cosolvent evaporation method. Approaches to enhance DTX entrapment efficiency (EE) and minimize particle size were investigated in
Hyo Won Seo et al.
Biomaterials, 34(11), 2748-2757 (2013-01-25)
The effectiveness of systemically administered anticancer treatments is limited by difficulties in achieving therapeutic doses within tumors, a problem that is complicated by dose-limiting side effects to normal tissue. To increase the efficacy and reduce the toxicity of systemically administered
Pengxiang Zhao et al.
Chemical communications (Cambridge, England), 49(31), 3218-3220 (2013-03-14)
"Click" chemistry now offers access to a great variety of triazoles, and the first example of a strategy to stabilize gold nanoparticles (AuNPs) with a new 1,2,3-triazole-mPEG ligand is developed here together with preliminary examples of possible applications.
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