强化和连续下游工艺
提高运营效率和灵活性，同时减少占地面积和成本
想要提高下游工艺效率？
由于业内迫切需要新疗法，同时渴望在降低成本的同时确保运营灵活性和生产力，生物制造工作流程转型加速已是毋庸置疑的事实。
工艺强化、封闭和连续的生物工艺是实现上述目标的基础策略。为进一步提升效率、速度、可持续性，降低尺寸和成本，这一策略广泛成功部署在下游组合中。
为帮助生物制药生产商实现强化、封闭、数字化增强或完全连续的工艺流程，全面提升运营效率和灵活性水平，DSP套件中包含了多个杠杆工具。
强化和连续下游 (DSP) 工艺
无论您采取何种路径，开发强化或连续的生物工艺，我们均可提供先进的下游工艺技术，助您达成纯化目标。
相关类别
一次性和复用性色谱系统是分离您的高价值分子的关键。
亲和色谱常用于捕获阶段，用于分离目标分子并减少加工体积。
离子交换（IEX）色谱根据目标分子和色谱树脂之间的电荷差异分离生物分子。
使用膜层析法进行捕获和精制，优化下游纯化。Natrix膜可提高经济性和设施效率。
提升过滤精密度：我们的切向流过滤产品可确保单克隆抗体、疫苗等的纯度，从一次性使用扩展至反复使用。
相关资源
- What is Multi Column Chromatography?
In this article, we will discuss one of the methods used to intensify the capture chromatography process: multi column chromatography (MCC).
- Mobius® Multi Column Capture System
The Mobius® Multi Column Capture system is designed as a fully automated, single-use solution to operate continuous closed capture chromatography.
- App Note: Multi Column Capture
Results from the multi-column capture (MCC) system implementation as part of a fully integrated downstream continuous manufacturing platform are reported here.
- Intensified Polishing Using Single-Pass Tangential Flow Filtration (SPTFF) with Anion Exchange Chromatography
In this app note, SPTFF preconcentration is used to intensify the anion exchange (AEX) polishing step in monoclonal antibody (mAb) processing for improved impurity removal and column productivity.
- Brochure: Process Development and Drug Manufacturing: Support Services
We provide comprehensive services for drug development and manufacturing, including technical and regulatory expertise and process development support.
- Article: pDADMAC Flocculation in Monoclonal Antibody Production Processes – Overcoming Regulatory Challenges with Quality Risk Management
Flocculants, like pDADMAC, remove cell debris during downstream monoclonal antibody production, but their adoption has been difficult due to perceived regulatory concerns.
相关网络研讨会
提高工艺效率并降低成本
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