离子交换色谱树脂_ESHMUNO® IEX 色谱树脂-默克生命科学
离子交换（IEX）色谱是一种根据表面净电荷分离目标分子和其它杂质的常用纯化方法。借助我们的多模式色谱树脂，我们的阴离子交换（AEX）和阳离子（CEX）树脂产品系列为单克隆抗体、疫苗、血浆DNA、血浆和其它模式提供高效的纯化解决方案。
Eshmuno® CMX混合模式树脂为单克隆抗体、融合蛋白和抗体药物偶联物（ADC）纯化以及低分子量杂质和宿主细胞蛋白（HCP）的分离带来了高选择性。
Eshmuno® CP-FT树脂在流通模式下可高效地去除单克隆抗体聚集物，从而实现了比传统结合/洗脱型阳离子色谱高10倍的负载能力。这可实现过程强化，同时减少下游单克隆抗体纯化的总体成本。
Eshmuno® CPS树脂为高盐浓度下的重组蛋白进料流带来了高动态结合能力和分离效率。这使高电导率进料流（电导率≥10 mS/cm）可以直接进料，无需稀释。
Eshmuno® CPX树脂可分离单克隆抗体单体和聚集体及其它杂质，即使在高负载下也是如此。 它为过程中间体的高分辨率纯化带来了高生产率。
Eshmuno® HCX树脂可以快速、高效、直接地捕获蛋白质，在高盐浓度下典型的离子交换和流通应用中具有出众的性能。
Eshmuno® S是一种强阳离子交换树脂，用于直接捕获重组蛋白和捕获蛋白A后快速高效的单克隆抗体纯化。
Eshmuno® Q是一种强阴离子树脂，为常见阴离子交换流通应用带来了出众的杂质去除率。
Fractogel® EMD IEX色谱树脂
所有 Fractogel® EMD 树脂都具有高选择性，同时具有一致的压力稳定性，从而实现了非常高的通量和绝佳的产率。树脂在高流速下的高结合能力节省了宝贵的时间，改善了工艺流程的经济性。Fractogel® 树脂有不同的微珠尺寸和多个官能团，以满足各种纯化需求：
Fractogel® 强阴离子交换剂
- Fractogel® EMD TMAE (S)树脂
- Fractogel® EMD TMAE (M)树脂
- Fractogel® EMD TMAE Hicap (M)树脂
- Fractogel® EMD TMAE Medcap (M) 树脂
Fractogel® 弱阴离子交换剂
Fractogel® 强阳离子交换剂
Fractogel® 弱阳离子交换剂
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- Biochromatography Portfolio
Bulk Resin, Membranes and Prepacked Columns
- Chromatography Purification Selection
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- Eshmuno® CMX Resin
A highly selective mixed mode chromatography resin for difficult to purify mAbs, ADCs and fusion proteins
- Eshmuno® CP‑FT Resin
A cation exchange resin specifically developed for the flow-through removal of aggregates using frontal chromatography
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High capacity and salt tolerance for recombinant protein purification
- Eshmuno® CPX
Efficient impurity removal and strong binding capacity at high flow rates
- Eshmuno® HCX Media
New, high salt-tolerant multi-mode chromatography resin
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For superior downstream mAB purification
- Eshmuno® Q Resin for Efficient AEX Chromatography
Eshmuno® Q resin is a strong anion exchange (AEX) resin, coupling our renowned tentacle structure with a hydrophilic polyvinyl ether base matrix
- Fractogel® Chromatography Resin
Fractogel® resins consist of synthetic methacrylate based polymeric beads providing excellent pressure stability resulting in high flow rates
- Robocolumn® and Minichrom Chromatography Columns
Small-scale prepacked chromatography columns for rapid process development, method optimization, parameter screening and sample preparation
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