用于生物加工的色谱系统
一次性及可重复使用色谱系统是成功分离您宝贵分子的关键因素。从中试到工业规模，我们的系统均旨在提供稳定、一致的性能，并满足您对工艺灵活性的需求。 此外，我们还提供种类齐全、无可比拟的色谱树脂和膜产品组合，并辅以无与伦比的应用和验证支持。凭借这一完整的产品阵容，我们将持续助力您提升生产力和工艺效率。我们的专家可协助您为色谱工艺选定最合适的产品。
Mobius® 多柱捕获系统
Mobius® 多柱捕获系统是一款全自动的一次性解决方案，用于进行连续闭环捕获色谱操作。该系统根据不断变化的色谱柱负载、缓冲进料罐负载以及树脂性能监测情况，实时管理工艺参数。凭借在线稀释功能和直观的软件，该三柱系统可对您的分批进料或灌注生物工艺中的捕获步骤进行全面控制。 Mobius® 多柱捕获系统适用于 50 L 至 2000 L 容积范围的生物反应器。了解更多关于多柱色谱的信息。
相关网络研讨会
多柱色谱是一种生物加工技术，其中将多根色谱柱串联安装，然后循环进行洗脱、再生和平衡。
一种新型蛋白A亲和膜的优势，该膜可作为高产率、真正的一次性色谱平台，用于强化单克隆抗体（mAb）的纯化。
CEX 流穿式前向色谱法用于去除单克隆抗体聚集物，以及影响这些聚集物去除效果的条件。
疫苗纯化用定制亲和色谱技术概述。
相关文件
- Application Note: Multi-Column Chromatography for Efficient Polishing Purification
The studies in this application note focus on Ion Exchange (IEX) chromatography in bind/elute mode using the Mobius® Multi Column Capture system.
- Application Note: Efficient Protein A Capture in Intensified Processes: Process Characterization and Scalability
Assess the efficiency of continuous mAb capture from a clarified and filtered harvest cell culture fluid (HCCF), using the Mobius® Multi Column Capture system and evaluate process scalability.
- Application Note: In-Line Dilution Capabilities of Mobius® Multi Column Capture System for Effective Buffer Management Strategies
Enhancing Intensified Chromatography Performance through Automated Buffer Dilution
- Application Note: Process Development and Scale-Up Strategy for the Mobius® Multi Column Capture System
A methodology for developing and scaling up a process for a multi-column capture operation using the Mobius® Multi Column Capture.
- Data Sheet: Mobius® Multi Column Capture System
The Mobius® Multi Column Capture system is designed as a fully automated, single-use solution to operate continuous closed capture chromatography.
- Data Sheet: Mobius® Chrom Systems
The Mobius® Chrom systems are a flexible, automated, single-use chromatography systems that enable consistent and reliable separation and purification.
- Application Note: Multi-Column Capture
Prototype Tests for Monoclonal Antibody Capture During Project nextBioPharmDSP (Horizon 2020).
- Technical Brief: Mobius® Breez Microbioreactor
Mixing and Gas Transfer in the Mobius® Breez Microbioreactor – How It Works?
- Spare Parts List: Mobius® Multi Column Capture System
To help you select and manage the spare parts required for your system, our experts have performed a risk assessment to determine which parts to keep in stock.
- Performance Guide: Mobius® Multi Column Capture System
The purpose of this document is to describe the performance of the Mobius® Multi Column Capture system and highlight the working principles of its innovative features.
- Data Sheet: CoPrime® Biochromatography Process-Scale System
Fully automated, configurable systems for biopharmaceutical manufacturing and cGMP process scale applications.
- Poster: Horizon 2020 - Fully Connected Single-use Downstream Platform for mAb Production
Within the biopharmaceutical industry, there is a significant shift toward higher productivity processes resulting in improved economics without compromising robustness. Therefore, integrated continuous production technologies are of greatest interest.
- Brochure: Process Development and Drug Manufacturing: Support Services
We provide comprehensive services for drug development and manufacturing, including technical and regulatory expertise and process development support.
- Application Note: Implementation of Multi-Column Chromatography Systems
The Multi-Column Capture (MCC) System enables efficient primary capture through three column operation, supporting continuous feedstream processing.
- Performance Guide: Mobius® Chrom 10 System
Discover Mobius® Chrom 10 system’s key performance highlights for scalable chromatography in clinical and commercial purification.
- Performance Guide: Mobius® Chrom 2 System
Discover the Mobius® Chrom 2 system, fully automated with operational flexibility, designed to reduce cross-contamination in scalable chromatography.