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T6260

Sigma-Aldrich

Sodium taurochenodeoxycholate

Synonym(s):

2-([3α,7α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid sodium salt, 3α,7α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt, Taurochenodeoxycholic acid sodium salt

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10 ML
¥3,557.12

About This Item

Empirical Formula (Hill Notation):
C26H44NNaO6S
CAS Number:
6009-98-9
Molecular Weight:
521.69
Beilstein:
3901205
MDL number:
MFCD00036745
UNSPSC Code:
41141802
PubChem Substance ID:
24900362
NACRES:
NA.25

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description

anionic

Quality Level

200

Assay

≥95.0% (TLC)

form

powder

mol wt

521.69 g/mol

CMC

4

HLB

20.1

functional group

sulfonic acid

shipped in

ambient

storage temp.

room temp

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阿霉素 盐酸盐 Pharmaceutical Secondary Standard; Certified Reference Material

PHR1789

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阿霉素 盐酸盐 98.0-102.0% (HPLC)

D1515

阿霉素 盐酸盐

阿霉素 盐酸盐 suitable for fluorescence, 98.0-102.0% (HPLC)

44583

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Doxorubicin Hydrochloride InSolution, ≥98%

504042

Doxorubicin Hydrochloride

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

application(s)

-

form

powder

form

powder

form

solid

form

liquid

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

200

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

-

grade

-

storage temp.

-10 to -25°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−70°C

General description

An ionic detergent used for solubilizing lipids and proteins.
Sodium taurochenodeoxycholate is a bile acid that can be used as an anionic detergent. [1]

Application

Sodium taurochenodeoxycholate has been used in a study to assess whether pancreatic β-cells contribute to BA-dependent regulation of glucose. [2] It has also been used in a study to investigate short-term feedback regulation of sodium taurocholate cotransporting polypeptide (Ntcp) by bile salts in vivo. [3]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000396232
    0000376041
    0000339363
    0000339361
    0000322171

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    M B Jiménez-Castro et al.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 12(12), 3257-3271 (2012-09-22)
    Numerous steatotic livers are discarded for transplantation because of their poor tolerance to ischemia-reperfusion (I/R). We examined whether tauroursodeoxycholic acid (TUDCA), a known inhibitor of endoplasmic reticulum (ER) stress, protects steatotic and nonsteatotic liver grafts preserved during 6 h in
    Noritaka Kawasaki et al.
    Scientific reports, 2, 799-799 (2012-11-15)
    Adipose tissue plays a central role in maintaining metabolic homeostasis under normal conditions. Metabolic diseases such as obesity and type 2 diabetes are often accompanied by chronic inflammation and adipose tissue dysfunction. In this study, we observed that endoplasmic reticulum
    Colin N Young et al.
    The Journal of clinical investigation, 122(11), 3960-3964 (2012-10-16)
    Although endoplasmic reticulum (ER) stress is a pathologic mechanism in a variety of chronic diseases, it is unclear what role it plays in chronic hypertension (HTN). Dysregulation of brain mechanisms controlling arterial pressure is strongly implicated in HTN, particularly in
    Kalaimathi Govindarajan et al.
    PloS one, 11(12), e0167319-e0167319 (2016-12-03)
    Disruptions to circadian rhythm in mice and humans have been associated with an increased risk of obesity and metabolic syndrome. The gut microbiota is known to be essential for the maintenance of circadian rhythm in the host suggesting a role
    B I Cohen et al.
    Journal of lipid research, 18(2), 223-231 (1977-03-01)
    Sterol metabolism studies using a combination of isotopic and chromatographic procedures were carried out in rats fed either a low-cholesterol stock diet or a stock diet containing 0.1% cholesterol. The primary bile acids, sodium taurochenodeoxycholate and sodium taurocholate, were added
    View All Related Papers

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