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T4009

Sigma-Aldrich

牛磺胆酸 钠盐 水合物

≥95% (HPLC)

别名:

2-[(3α,7α,12α-三羟基-24-氧基-5β-胆烷-24-基)氨基]乙磺酸, 3α,7α,12α-三羟基-5β-胆烷-24-酸N-(2-磺乙基)酰胺, 牛胆酸钠 水合物

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About This Item

经验公式（希尔记法）:
C26H44NNaO7S · xH2O
CAS号:
345909-26-4
分子量:
537.68 (anhydrous basis)
EC 号:
205-653-7
MDL编号:
MFCD00150819
UNSPSC代码:
12161900
PubChem化学物质编号:
24900186
NACRES:
NA.25

生物来源

synthetic (organic)

质量水平

200

描述

anionic

方案

≥95% (HPLC)

表单

powder

分子量

micellar avg mol wt 2100

聚集数

4

CMC

3-11 mM (20-25°C)

官能团

sulfonic acid

运输

ambient

储存温度

room temp

SMILES字符串

[Na+].[H]O[H].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCS([O-])(=O)=O

InChI

1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1

InChI key

RDAJAQDLEFHVNR-NEMAEHQESA-M

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相关类别

一般描述

巯基乙酸钠水合物是一种胆汁酸，有洗涤剂作用。

应用

巯基乙酸钠水合物被用来评估植物纤维组织对胆汁酸和盐的吸收度。 它在一项研究中被用来检测血清和空肠液中的共轭和非共轭胆汁酸。
阴离子洗涤剂用于蛋白质溶解。

生化/生理作用

非硫化胆盐，是胆盐排出泵/Pgp（BSEP/spgp)姐妹，Na(+)/牛磺胆酸协同转运蛋白和MRP3进入肝脏系统的生理性转运底物。

制备说明

从胆酸合成

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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分析证书(COA)

Lot/Batch Number
0000398874
0000396649
0000396657
0000396651
0000396650

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Studies on the adsorption of bile salts to non-absorbed components of diet.
M A Eastwood et al.
Biochimica et biophysica acta, 152(1), 165-173 (1968-01-10)
Joseph J Orsini et al.
Clinica chimica acta; international journal of clinical chemistry, 413(15-16), 1270-1273 (2012-05-03)
We sought to modify a previously published tandem mass spectrometry method of screening for 5 lysosomal storage disorders (LSDs) in order to make it better suited for high-throughput newborn screening. Two 3-mm dried blood spot (DBS) punches were incubated, each
A Tangerman et al.
Clinica chimica acta; international journal of clinical chemistry, 159(2), 123-132 (1986-09-15)
A reliable method is described for the determination of conjugated and unconjugated bile acids in serum and jejunal fluid. Bile acids are extracted using reverse-phase octadecylsilane bonded silica cartridges and are separated into their unconjugated and conjugated fractions using the
Yanxia Wei et al.
BMC infectious diseases, 19(1), 46-46 (2019-01-13)
Clostridium difficile (C. difficile) is a main cause of antibiotic-associated diarrhoea in humans. Several studies have been performed to reveal the prevalence rate of C. difficile in cats and dogs. However, little is known about the epidemiology of C. difficile
Studies on the Antibacterial Properties of the Bile Acids and some Compounds Derived from Cholanic Acid
M. Stacey and M. Webb
Proc. Royal Soc. Lond. B., 134, 523-523 (1947)
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