580549
牛磺酸去氧胆酸，钠盐
Tauroursodeoxycholic is a detergent useful for the solubilization of lipids and membrane-bound proteins.
别名:
牛磺酸去氧胆酸，钠盐, 牛磺熊脱氧胆酸钠
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关于此项目
经验公式（希尔记法）:
C26H44NO6S · Na
化学文摘社编号:
分子量:
521.69
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.21
产品名称
牛磺酸去氧胆酸，钠盐, Tauroursodeoxycholic is a detergent useful for the solubilization of lipids and membrane-bound proteins.
SMILES string
[S](=O)(=O)(O)CCNC(=O)CC[C@H]([C@@H]1[C@@]2(C(C3[C@H](C[C@H]4[C@@](C3CC2)(CC[C@H](C4)O)C)O)CC1)C)C
InChI
1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20?,21?,22+,24?,25+,26-/m1/s1
InChI key
BHTRKEVKTKCXOH-AYSJQVDDSA-N
description
RTECS - KI7372500
assay
≥97% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
water: 100 mg/mL
shipped in
ambient
storage temp.
15-25°C
Quality Level
Application
- 内质网应激的抑制以及血管紧张素转换酶2的激活：预防1型糖尿病大鼠内皮功能障碍的新方法: 本研究的亮点是牛磺脱氧胆酸钠减少内质网应激的功效，表明其在预防糖尿病血管并发症方面的实用性((Gaikwad AB et al., 2022)。
Disclaimer
毒性：标准处理（A）
General description
用于溶解脂质和膜结合蛋白质的洗涤剂。对大鼠体内的疏水性胆盐具有冷冻保护作用。据报道也可抑制体外胃蛋白酶活性。
Other Notes
Ozcan, U., et al. 2006.Science313, 1137.
Miyake, H., et al. 1999.Dig.Dis.Sci.44, 197.
Eto, T. and Tompkins, R.K.1985.Am. J. Surg.150, 564.
Miyake, H., et al. 1999.Dig.Dis.Sci.44, 197.
Eto, T. and Tompkins, R.K.1985.Am. J. Surg.150, 564.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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