所有图片(7)

主要文件

COO原产地证书/COA分析证书

查看所有文档

G0759

甘氨鹅脱氧胆酸钠

Name: 甘氨鹅脱氧胆酸钠
Brand: SIGMA

别名:

3α,7α-二羟基-5β-胆烷酸 N-（羧甲基）酰胺钠盐, N-(3α,7α-二羟基-24-氧代胆烷-24-基)甘氨酸钠盐, 甘氨鹅脱氧胆酸钠盐

登录查看公司和协议定价

所有图片(7)

About This Item

经验公式（希尔记法）:

C₂₆H₄₂NNaO₅

CAS号:

16564-43-5

分子量:

471.61

Beilstein:

3847290

MDL编号:

MFCD00036743

UNSPSC代码:

12161900

PubChem化学物质编号:

24895023

NACRES:

NA.25

推荐产品

Slide 1 of 10

1 of 10

Sigma-Aldrich

50534

甘氨鹅脱氧胆酸钠

Sigma-Aldrich

T6260

牛磺鹅去氧胆酸钠

Sigma-Aldrich

G2878

甘胆酸水合物

Millipore

360512

Glycocholic Acid, Sodium Salt

Sigma-Aldrich

F0152

Nalgene^® baffled shake flask

Sigma-Aldrich

G7132

甘胆酸钠水合物

Sigma-Aldrich

CBA

胆汁酸，结合型

Millipore

361311

脱氧甘胆酸钠盐

Sigma-Aldrich

C4706

三 2-羰基乙基磷盐酸盐盐酸盐

Sigma-Aldrich

T0875

牛磺脱氧胆酸钠水合物

描述

anionic

质量水平

200

表单

powder

分子量

471.61 g/mol

技术

HPLC: suitable
protein quantification: suitable

官能团

sulfonic acid

运输

ambient

储存温度

room temp

SMILES字符串

[Na+].C[C@H](CCC(=O)NCC([O-])=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C26H43NO5.Na/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29;/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);/q;+1/p-1/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-;/m1./s1

InChI key

AAYACJGHNRIFCT-YRJJIGPTSA-M

正在寻找类似产品? 访问产品对比指南

一般描述

甘氨鹅脱氧胆酸盐 (GCDC) 是一种有毒的疏水性胆汁盐。

应用

甘氨鹅去氧胆酸钠已被用作 de Man、Rogosa 和 Sharpe (MRS) 琼脂中的添加剂，用于胆汁酸解偶联，测定菌株解偶联特定胆汁酸的能力。

甘氨鹅脱氧胆酸钠已可用于评估胆汁盐诱导的DNA损伤的修复。它还被用于研究A型产气荚膜梭菌( Clostridium perfringens ）在人胆汁盐存在下的肠毒素产生。

生化/生理作用

甘氨鹅脱氧胆酸盐 (GCDC) 可诱导部分由 Fas 介导的肝细胞凋亡。

替代产品

产品编号

说明

价格

50534

甘氨鹅脱氧胆酸钠, ≥97.0% (TLC)

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000427454

0000425729

0000396759

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Repair of DNA damage induced by bile salts in Salmonella enterica.

Ana I Prieto et al.

Genetics, 174(2), 575-584 (2006-08-05)

Exposure of Salmonella enterica to sodium cholate, sodium deoxycholate, sodium chenodeoxycholate, sodium glycocholate, sodium taurocholate, or sodium glycochenodeoxycholate induces the SOS response, indicating that the DNA-damaging activity of bile resides in bile salts. Bile increases the frequency of GC -->

Sirt6 opposes glycochenodeoxycholate-induced apoptosis of biliary epithelial cells through the AMPK/PGC-1α pathway.

Jiye Li et al.

Cell & bioscience, 10, 43-43 (2020-03-25)

Induction of biliary epithelial cell apoptosis by toxic bile acids is involved in the development of cholestatic disease, but the underlying molecular mechanism is not clear. The purpose of this study was to investigate the molecular mechanisms involved in Sirt6

Growth, sporulation and enterotoxin production by Clostridium perfringens type A in the presence of human bile salts.

N L Heredia et al.

FEMS microbiology letters, 68(1), 15-21 (1991-11-01)

The effect of human bile juice and bile salts (sodium cholate, sodium taurocholate, sodium glycochenodeoxycholate and sodium chenodeoxycholate) on growth, sporulation and enterotoxin production by enterotoxin-positive and enterotoxin-negative strains of Clostridium perfringens was determined. Each bile salt inhibited growth to

Comparison of Microneutralization and Histo-Blood Group Antigen-Blocking Assays for Functional Norovirus Antibody Detection.

Robert L Atmar et al.

The Journal of infectious diseases, 221(5), 739-743 (2019-10-16)

The development of an in vitro cultivation system for human noroviruses allows the measurement of neutralizing antibody levels. Serum neutralizing antibody levels were determined using a GII.4/Sydney/2012-like virus in human intestinal enteroids in samples collected before and 4 weeks after

Glycochenodeoxycholate promotes the metastasis of gallbladder cancer cells by inducing epithelial to mesenchymal transition via activation of SOCS3/JAK2/STAT3 signaling pathway.

Hui Wang et al.

Journal of cellular physiology, 235(2), 1615-1623 (2019-07-28)

The incidence of gallbladder cancer (GBC) is relatively rare but a high degree of malignancy. The migration and invasion potential of GBC severely affects the prognosis of patients with GBC. Glycochenodeoxycholate (GCDC) is one of the most important components in

查看所有相关文献

商品

Probiotics and Human Health

Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.

实验方案

HPLC Separation of Bile Acids with Ascentis Express C18

Investigate bile acid roles in gut hormone profiles and glycemic control, vital for clinical labs exploring potential mechanisms.

主要文件