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SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

别名:
PAI, PAI-1, PAI1, PLANH1
物种:
UniProtKB ID:
基因ID:
  • Human(5054) Summary: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(18787) serine (or cysteine) peptidase inhibitor, clade E, member 1
  • Rat(24617) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • cow(281375) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Zebrafish(100136840) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • domestic guinea pig(100725387) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • naked mole-rat(101703903) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Domestic Rabbit(100009588) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • dog(403476) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • domestic cat(100127105) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

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ELISA

货号
说明
物种
人 PAI-1 ELISA 试剂盒, for serum, plasma, cell culture supernatant.,
物种
human
恒河猴PAI-1 ELISA试剂盒, for cell culture supernatants, plasma, and serum samples,
物种

Antibodies

货号
说明
物种反应性
应用
Anti-PAI-1 Mouse mAb (MA-33B8), liquid, ≥90% (SDS-PAGE), clone MA-33B8,
物种反应性
human, rabbit
应用
Anti-SERPINE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-PAI-1 (Ab-1) Mouse mAb (2), lyophilized, clone 2, Calbiochem®,
物种反应性
human
应用
Anti-SERPINE1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Monoclonal Anti-SERPINE1 antibody produced in mouse, clone 1D5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
flow cytometry

immunohistochemistry

western blot

Proteins

货号
说明
物种
血纤维蛋白溶酶原激活物抑制剂1(PAI-1) 人, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Serpine1,
物种
mouse
MISSION® esiRNA, targeting human SERPINE1,
物种
human