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种属反应性
human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
capture ELISA: suitable
输入
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 35 pg/mL
standard curve range: 0.102-25 ng/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... SERPINE1(5054)
一般描述
The Human PAI-1 (plasminogen activator inhibitor-1) ELISA (enzyme-linked immunosorbent assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human PAI-1 in serum, plasma, cell culture supernatants. PAI-1 is 45kDa serine proteinase inhibitor. It inhibits plasmogen activator and affects the fibrinolytic process, as a result of which it leads to thrombosis. Reduced fibrinolysis is observed in ischemic heart disease. While elevated PAI-1 levels are noticed in myocardial infarction. PAI-1 is associated with various physiological processes including wound healing, sepsis, insulin resistance, obesity, atherosclerosis, tumor angiogenesis, bone remodeling, asthma, rheumatoid arthritis, glomerulonephritis and chronic stress.
免疫原
Recombinant Human PAI-I
应用
请参考Protocol了解详情。
其他说明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
Pleiotropic functions of plasminogen activator inhibitor-1
Lijnen, HR
Journal of Thrombosis and Haemostasis, 3(1), 35-45 (2005)
María Paniagua-Sancho et al.
American journal of nephrology, 52(9), 714-724 (2021-09-15)
Acute kidney injury (AKI) is a threatening, multiaetiological syndrome encompassing a variety of forms and damage patterns. AKI lacks sufficiently specific diagnostic tools to evaluate the distinct combination of pathophysiological events underlying each case, which limits personalized and optimized handling.
Brain Edema XI: Proceedings of the 11th International Symposium, 277-277 (1999)
Jessica Perugini et al.
Scientific reports, 12(1), 8331-8331 (2022-05-19)
To establish whether obesity involves activation of endogenous ciliary neurotrophic factor (CNTF) signalling, we evaluated its plasma levels in patients with obesity and correlated its values with the major clinical and haematological indices of obesity, insulin resistance and systemic inflammation.
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