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Merck
CN

HTR4

5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

别名:
5-HT4, 5-HT4R
物种:
Human HTR4 (3360), Mouse Htr4 (15562), Rat Htr4 (25324), Horse HTR4 (100034053), domestic cat HTR4 (101088723), sheep HTR4 (101117928), cow HTR4 (317708), domestic guinea pig Htr4 (100135548), chicken HTR4 (416150), dog HTR4 (489198)
UniProtKB ID:
Q13639, Q546Q1, Q684M0, Q712M9, Q96KH9, Q96KI0, Q9H199, Q9NY73
基因ID:
  • Human(3360) Summary: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
  • Mouse(15562) 5 hydroxytryptamine (serotonin) receptor 4
  • Rat(25324) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • Horse(100034053) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • domestic cat(101088723) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • sheep(101117928) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • cow(317708) 5-hydroxytryptamine (serotonin) receptor 4
  • domestic guinea pig(100135548) 5 hydroxytryptamine (serotonin) receptor 4
  • chicken(416150) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • dog(489198) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • naked mole-rat(101707865) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

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Small Molecule - Agonist

货号
说明
物种
SML1504
Tegaserod maleate, ≥98% (HPLC),
物种
human
32473
甲氧氯普胺, VETRANAL®, analytical standard,
物种
human
M1824990
甲氧氯普胺, European Pharmacopoeia (EP) Reference Standard,
物种
human
BP357
甲氧氯普胺 盐酸盐, British Pharmacopoeia (BP) Reference Standard,
物种
human
M0763
甲氧氯普胺 盐酸盐, solid,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
D9190
DCEBIO, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
S3313
SB-204070 盐酸盐, solid, ≥97% (HPLC),
物种
human
M7319
ML 10302, ≥98%, solid,
物种
rat
32473
甲氧氯普胺, VETRANAL®, analytical standard,
物种
human
G5918
GR 113808, ≥98% (HPLC), solid,
物种
rat, human
M1824990
甲氧氯普胺, European Pharmacopoeia (EP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
SAB4501480
Anti-5-HT-4 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
western blot
HPA040591
Anti-HTR4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
SAB2101109
Anti-HTR4 antibody produced in rabbit, affinity isolated antibody,
物种反应性
dog, human, rabbit
应用
western blot

Small Molecule - Blocker

货号
说明
物种
T3146
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
物种
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
物种
human
F132
氟西汀 盐酸盐, solid,
物种
human
S6319
盐酸舍曲林 盐酸盐, ≥98% (HPLC),
物种
human
C7861
氢溴酸西酞普兰 氢溴酸盐, ≥98% (HPLC),
物种
human

Small Molecule - Ligand

货号
说明
物种
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物种
human

Small Molecule - Metabolite

货号
说明
物种
H8876
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物种
human

Small Molecule - Precursor

货号
说明
物种
H9772
5-羟基L-色氨酸, powder,
物种
human

esiRNA

货号
说明
物种
EHU070651
MISSION® esiRNA, targeting human HTR4,
物种
human