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Merck
CN

DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

别名:
DNMT3A2, M.HsaIIIA
物种:
UniProtKB ID:
基因ID:
  • Human(1788) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(13435) DNA methyltransferase 3A
  • Rat(444984) DNA (cytosine-5-)-methyltransferase 3 alpha
  • sheep(100500776) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Domestic Rabbit(100344715) DNA (cytosine-5-)-methyltransferase 3 alpha
  • cow(359716) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic cat(100510798) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Horse(100055881) DNA (cytosine-5-)-methyltransferase 3 alpha
  • dog(482996) DNA (cytosine-5-)-methyltransferase 3 alpha
  • naked mole-rat(101718745) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic guinea pig(100721625) DNA (cytosine-5-)-methyltransferase 3 alpha
  • chicken(421991) DNA (cytosine-5-)-methyltransferase 3 alpha

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Antibodies

货号
说明
物种反应性
应用
Anti-DNMT3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
Anti-DNMT3A antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
western blot
Anti-DNMT3A2 Antibody, from rabbit,
物种反应性
human
应用
ELISA
immunocytochemistry

western blot
Anti- DNMT3A antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-DNMT3A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, human, mouse, rat
应用
ELISA
western blot

Small Molecule - Inhibitor

货号
说明
物种
5-氮杂-2′-脱氧胞苷, ≥97%,
物种
human
5-阿扎胞苷, Hybri-Max, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
物种
human
阿扎胞苷, United States Pharmacopeia (USP) Reference Standard,
物种
human
阿扎胞苷, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
5-阿扎胞苷, ≥98% (HPLC),
物种
human

Proteins

货号
说明
物种
DNMT3a Active human, recombinant, expressed in baculovirus infected insect cells,
物种
human
DNMT3A/DNMT3L,活性,人, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human DNMT3A,
物种
human
MISSION® esiRNA, targeting mouse Dnmt3a,
物种
mouse