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Merck
CN

V900750

吲哚-3-羧酸

Vetec, reagent grade, 98%

别名:

β-吲哚羧酸, 3-吲哚甲酸, 3-吲哚羧酸, 3-羧基吲哚, 吲哚-β-羧酸

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关于此项目

经验公式(希尔记法):
C9H7NO2
化学文摘社编号:
分子量:
161.16
EC Number:
212-231-6
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
129435
MDL number:
Assay:
98%
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InChI

1S/C9H7NO2/c11-9(12)7-5-10-8-4-2-1-3-6(7)8/h1-5,10H,(H,11,12)

InChI key

KMAKOBLIOCQGJP-UHFFFAOYSA-N

SMILES string

OC(=O)c1c[nH]c2ccccc12

grade

reagent grade

product line

Vetec

assay

98%

mp

232-234 °C (dec.) (lit.)

Application

作为反应物用于制备:
  • 抗癌剂
  • 氨基酸和肽的衍生物
  • 5-羟色胺5-HT4受体拮抗剂
  • 主要的酰基脲类
  • 在Hedgehog途径中,Gli1介导的转录的抑制剂
  • 5-羟色胺5-HT6拮抗剂
  • 超晚期抗原-4(VLA-4)拮抗剂
  • EphB3受体酪氨酸激酶抑制剂
  • 阿尔茨海默病的潜在治疗药物
  • 乙烯基酯假三肽蛋白酶体抑制剂

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mu-Yang Wang et al.
Journal of integrative plant biology, 54(7), 471-485 (2012-05-26)
Camalexin (3-thiazol-2'-yl-indole) is the major phytoalexin found in Arabidopsis thaliana. Several key intermediates and corresponding enzymes have been identified in camalexin biosynthesis through mutant screening and biochemical experiments. Camalexin is formed when indole-3-acetonitrile (IAN) is catalyzed by the cytochrome P450
J Hagemeier et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(2), 753-758 (2001-01-03)
The chemical structures and accumulation kinetics of several major soluble as well as wall-bound, alkali-hydrolyzable compounds induced upon infection of Arabidopsis thaliana leaves with Pseudomonas syringae pathovar tomato were established. All identified accumulating products were structurally related to tryptophan. Most
M U Ahmad et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 23(9), 841-847 (1985-09-01)
The nitrosation of gramine, a tertiary amine alkaloid present in barley malt, was carried out by reaction with sodium nitrite in buffered acetic acid (pH 3.4) for 1 hr at room temperature. Two major non-volatile products of the nitrosation reaction
Jamil A Shilpi et al.
Fitoterapia, 81(6), 536-539 (2010-01-26)
Phytochemical investigation of the stem bark of Trewia nudiflora led to the isolation of two new cardenolides, trewianin (1) and trewioside (2), along with scopoletin (3) and indole-3-carboxylic acid (4). Structures were established by 1D- and 2D NMR spectroscopy, HR-MS
Ferdinand S Melkonyan et al.
The Journal of organic chemistry, 73(11), 4275-4278 (2008-05-13)
A variety of N-alkylated and N-arylated derivatives of methyl 1 H-indole-3-carboxylate were synthesized efficiently via Ullmann-type intramolecular arylamination, using the CuI-K 3PO 4-DMF system. This catalytic amination procedure can be performed with good to high yields under mild conditions under

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