推荐产品
质量水平
检测方案
97%
形式
solid
mp
193-198 °C (lit.)
SMILES字符串
O=Cc1c[nH]c2ccccc12
InChI
1S/C9H7NO/c11-6-7-5-10-9-4-2-1-3-8(7)9/h1-6,10H
InChI key
OLNJUISKUQQNIM-UHFFFAOYSA-N
正在寻找类似产品? 访问 产品对比指南
一般描述
吲哚-3-甲醛可进行席夫碱缩合，从而形成多功能二氧化硅纳米载体和磁性纳米粒子。
应用
其是制备如下化合物所需的反应物：
- 镇痛剂
- 降糖药
- 色氨酸双加氧酶抑制剂吡啶基-乙烯基-吲哚（作为潜在的抗癌免疫调节剂）
- 抗菌和抗真菌剂
- 抗变形虫药和细胞毒性剂
- 登革病毒蛋白酶的抑制剂（在细胞培养中具有抗病毒活性）
- 姜黄素类似物（可能的抗增殖 & 抗炎剂）
- Bcl-2家族蛋白的抑制剂
- RNA聚合酶IIC末端结构域的抑制剂（作为抗肿瘤剂）
- TNF-α和IL-6的抑制剂（具有抗结核活性）
吲哚-3-甲醛可用于制备带有NR1R2基团的吲哚植物抗毒素环油菜素的类似物。它也被用作合成高阶吲哚的起始材料，包括异吲哚[2,1-a]吲哚、 aplysinopsins、 以及4-取代四氢苯并[cd]吲哚。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Qiu-Yun Chen et al.
Colloids and surfaces. B, Biointerfaces, 114, 158-163 (2013-11-05)
Multifunctional silica nano-vehicles (SiO2@indol-IL) and magnetic nanoparticles (Fe3O4@indol-IL) were constructed through the Schiff bases condensation of indole-3-carboxaldehyde and 4-acetyl-N-allyl pyridinium chloride (ILs) with the amine groups of silica and magnetic nanoparticles. SiO2@indol-IL can inhibit the proliferation of HepG-2 cells in
Heterocycles, 38, 1479-1479 (1994)
Indian J. Chem. B, 33, 4-4 (1994)
Mariana Budovská et al.
Bioorganic & medicinal chemistry, 21(21), 6623-6633 (2013-09-10)
An effective synthesis of analogs of the indole phytoalexin cyclobrassinin with NR1R2 group instead of SCH3 was developed starting from indole-3-carboxaldehyde. The target compounds were prepared by spirocyclization of 1-Boc-thioureas with the formation of isolable spiroindoline intermediates, followed by the
Tian-Lin Yang et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 67(2), 568-571 (2006-09-22)
A new Schiff base ligand with tripodal structure, N,N',N''-tri-(3-indolemethanal)-triaminotriethylamine (L), and its complex with terbium was synthesized. The complex was characterized by element analysis, IR spectra, mass spectra, thermal analysis and molar conductivity. The terbium ion was found to coordinate
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门