HybridSPE^®-PLus 96-Well solid phase extraction (SPE) Plate

This article highlights the impact that sample matrix effects can have on LC/MS response and discusses two novel approaches to reduce it.

Using HybridSPE-Phospholipid, Ascentis Express, and Other LC-MS Workflow Components

Immunoassay-based methods for digitoxin or digoxin exist, but are time consuming, labor intensive, and not selective due to similarities in their chemical structures.

LC/MS/MS Analysis of Interacting Cardiac Drugs Digoxin, Quinidine, Amiodarone and Verapamil on Titan™ C18

Small molecules are ions and compounds of molecular weight typically less than 900 daltons. These compounds can be effectively separated and analyzed by HPLC, UHPLC and LC-MS using mainly silica particles or monolithic stationary phases with a broad range of column chemistries (modifications).

小分子特指低分子量化合物（通常小于900道尔顿），分离小分子方法包括高效液相色谱(HPLC)、液相(LC)、气相(GC)、薄层色谱(TLC) 和毛细管电泳(CE)。此外，还可通过磁共振波谱法(NMR)或 质谱法(MS)等方法鉴定小分子。

Small molecules are ions and compounds of molecular weight typically less than 900 daltons. These compounds can be effectively separated and analyzed by HPLC, UHPLC and LC-MS using mainly silica particles or monolithic stationary phases with a broad range of column chemistries (modifications).

固相萃取(SPE)是一种用在色谱分析（如 HPLC、GC、TLC 色谱）前快速、选择性制备和纯化样品的技术，主要用于置换样品基质、浓缩分析物、去除干扰成分和污染物，以改善数据结果、保护分析色谱柱。