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形式
solid
质量水平
颜色
white
溶解性
methanol: soluble 50 mg/ml, clear to hazy, colorless
H2O: soluble
SMILES字符串
Cl[H].OC(CCN1CCCCC1)(C2CCCCC2)c3ccccc3
InChI
1S/C20H31NO.ClH/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21;/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2;1H
InChI key
QDWJJTJNXAKQKD-UHFFFAOYSA-N
基因信息
human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131) , CHRM4(1132) , CHRM5(1133)
应用
DL-三己基哌啶盐酸盐已被用于开发基于端柱电化学发光（ECL）的毛细管区带电泳。
生化/生理作用
已知DL-三己基哌啶盐酸盐（盐酸苯海索）起抗毒蕈碱剂和中枢性抗胆碱能作用。它可用于控制所有帕金森病类型的症状，例如特发性和脑后动脉硬化。盐酸苯海索对副交感神经系统起抑制作用。
毒蕈碱型乙酰胆碱受体拮抗剂
制备说明
DL-三己基哌啶盐酸盐可溶于水。它以50 mg/ml的浓度溶于甲醇中，可得到澄清至浑浊的无色溶液。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
T Hayakawa et al.
Clinical and experimental pharmacology & physiology, 26(5-6), 421-425 (1999-07-01)
1. Effects of anti-Parkinsonian drugs on neurobehavioural changes induced by bilateral lesions of dopaminergic neurons were investigated in rats. 2. Dopaminergic neurons in rats were lesioned bilaterally by injection of 6-hydroxydopamine (6-OHDA; 8 micrograms) into the medial forebrain bundle at
Y Kimura et al.
Brain research, 834(1-2), 6-12 (1999-07-17)
An amnesic effect of anticholinergic drugs was previously described from several behavioral studies. We examined this effect induced by trihexyphenidyl and biperiden, clinically used in the parkinsonism and schizophrenic patients, by using passive avoidance tasks. Both of these drugs (0.1-10
Determination of benzhexol hydrochloride by capillary zone electrophoresis with an end-column electrochemiluminescence detection.
Yan, J., et al.
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 76(1), 11-16 (2004)
H E Shannon et al.
The Journal of pharmacology and experimental therapeutics, 290(2), 901-907 (1999-07-20)
The purpose of our studies was to determine the effects of muscarinic receptor agonists on conditioned avoidance responding in the rat. Rats were trained to avoid or escape an electric shock delivered to the feet in a discrete trial procedure.
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