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Merck
CN

CHRM4

cholinergic receptor, muscarinic 4

别名:
HM4, M4R
物种:
Human CHRM4 (1132), Mouse Chrm4 (12672), Rat Chrm4 (25111), domestic guinea pig Chrm4 (100714736), naked mole-rat Chrm4 (101726411), Domestic Rabbit CHRM4 (100008791), dog CHRM4 (611314), cow CHRM4 (512928), sheep CHRM4 (101114554), domestic cat CHRM4 (101088360)
UniProtKB ID:
P08173, B2RPP4, Q0VD60, Q4VBK7
基因ID:
  • Human(1132) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
  • Mouse(12672) cholinergic receptor, muscarinic 4
  • Rat(25111) cholinergic receptor, muscarinic 4
  • domestic guinea pig(100714736) cholinergic receptor, muscarinic 4
  • naked mole-rat(101726411) cholinergic receptor, muscarinic 4
  • Domestic Rabbit(100008791) cholinergic receptor, muscarinic 4
  • dog(611314) cholinergic receptor, muscarinic 4
  • cow(512928) cholinergic receptor, muscarinic 4
  • sheep(101114554) cholinergic receptor, muscarinic 4
  • domestic cat(101088360) cholinergic receptor, muscarinic 4
  • chicken(423195) cholinergic receptor, muscarinic 4

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Small Molecule - Agonist

货号
说明
物种
A2251
乙酰基-β-氯化甲基胆碱, ≥98% (TLC), powder,
物种
human
O100
氧化震颤素M, solid,
物种
human
C4382
卡巴胆碱, ≥98% (titration), crystalline,
物种
human, mouse, rat

Small Molecule - Antagonist

货号
说明
物种
B1390
比沙可啶, analytical standard, for drug analysis,
物种
human
T9778
托吡卡胺, solid,
物种
human
P8891
溴丙胺太林, ≥97% (TLC), powder,
物种
human
O2881
盐酸奥昔布宁, ≥98% (TLC), powder,
物种
human
D7909
Dicyclomine hydrochloride, ≥99% (TLC), powder,
物种
human

Antibodies

货号
说明
物种反应性
应用
MAB1578
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2, clone 18C7.2, Chemicon®, from mouse,
物种反应性
monkey
应用
immunohistochemistry
immunoprecipitation (IP)
western blot
ZMS1165
Anti-CHRM4 Antibody, clone 18C7.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
ELISA
affinity binding assay
immunocytochemistry
western blot
SAB4300824
Anti-CHRM4 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
western blot
MAB1576
毒蕈碱乙酰胆碱受体m4抗体，克隆17F10.2, purified antibody, clone 17F10.2, Chemicon®,
物种反应性
monkey, mouse, rat
应用
immunocytochemistry
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

货号
说明
物种
A8404
盐酸阿米替林 盐酸盐, ≥98% (TLC), powder,
物种
human
D4526
多塞平 盐酸盐, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
物种
human

esiRNA

货号
说明
物种
EMU046221
MISSION® esiRNA, targeting mouse Chrm4,
物种
mouse